Most polyp segmentation methods use CNNs as their backbone, leading to two key issues when exchanging information between the encoder and decoder: 1) taking into account the differences in contribution between different-level features; and 2) designing effective mechanism for fusing these features. Different from existing CNN-based methods, we adopt a transformer encoder, which learns more powerful and robust representations. In addition, considering the image acquisition influence and elusive properties of polyps, we introduce three novel modules, including a cascaded fusion module (CFM), a camouflage identification module (CIM), a and similarity aggregation module (SAM). Among these, the CFM is used to collect the semantic and location information of polyps from high-level features, while the CIM is applied to capture polyp information disguised in low-level features. With the help of the SAM, we extend the pixel features of the polyp area with high-level semantic position information to the entire polyp area, thereby effectively fusing cross-level features. The proposed model, named Polyp-PVT, effectively suppresses noises in the features and significantly improves their expressive capabilities. Extensive experiments on five widely adopted datasets show that the proposed model is more robust to various challenging situations (e.g., appearance changes, small objects) than existing methods, and achieves the new state-of-the-art performance. The proposed model is available at https://github.com/DengPingFan/Polyp-PVT.