Editor’s Focus

Abstract

Gidvani and colleagues hypothesized that maternal surfactant protein A (SP-A) improves survival in newborn mice by optimizing milk immunoprotection. Immunologic responses to a novel antigen and to a nonhygienic environment were evaluated in wildtype and SP-A-null murine dams.The results appear to demonstrate that maternal SP-A attenuates a proinflammatory cytokine profile in milk. See page 135