Editorial

Syringoleosides A–H, Secoiridoids from Syringa dilatata Flowers and Their Inhibition of NO Production in LPS-Induced RAW 264.7 Cells

“…These cells were treated with the fractions and isolated compounds (10,20,40,50,80, and 100 μM). The isolated secoiridoids showed no cytotoxicity at concentrations lower than 100 (1,4,5,7,8,10,11,13) or 50 (2,3,6,12) μM. Table 3 shows that the LPS-treated compound group included suppressed NO formation.…”

“…Protecting the sovereignty of biological resources in the country of origin is important, as stated in the Nagoya protocol. This protocol was established for the fair and equitable distribution of profits resulting from the use of natural resources and is intended to contribute to the conservation and sustainable use of biodiversity. With this protocol in force, research using domestic native species has become a key issue.…”

“…The 1 H NMR and 13 C NMR spectra of compound 3 (Figures S14 and S15, Supporting Information) were analogous to those of compounds 1 and 2, but their phenylethanoid moiety was replaced by a coniferyl alcohol moiety. In the 1 7‴) representing a phenylethanol with a pdisubstituted benzene structure were detected. In the 13 S24 and S25, Supporting Information) were nearly identical to those of 4, except for the binding site of a secoiridoid glycoside unit.…”

“…Additionally, the 1 H NMR signals of the hexose and phenylethanoid moieties were observed. In the1 H NMR spectrum, signals of a hemiacetal (δ H 4.77, d, J = 7.2 Hz, H-1″), four oxygenated methines (δ H 4.22, overlapped, H-4″; 4.18, overlapped, H-2″; 3.95, overlapped, H-3″, 5″), and an oxygenated methylene (δ H 4.87, dd, J = 10.4, 9.0 Hz, H-6″a; 4.61, dd, J = 10.4, 5.4 Hz, H-6″b) representing a hexose moiety and four olefinic methines (δ H 7.22, d, J = 8.4 Hz, H-2‴, 6‴; 7.11, d, J = 8.4 Hz, H-3‴, 5‴) from a p-disubstituted benzene unit, an oxygenated methylene (δ H 4.77, br d, J = 7.2 Hz, H-8‴a; 3.87, dd, J = 16.8, 7.2 Hz, H-8‴b), and a methylene (δ H 2.94, m, H-…”