This paper presents a comprehensive review of the research literature on ambiguous losses, focusing on the psychological impact of uncertainty and the associated unresolved circumstances. The research method involves synthesizing data from various sources, including academic articles, books, and case studies, accessed through databases like PubMed, Scopus, Web of Science, and PsycINFO. The study underscores the need for specialized therapeutic methods and comprehensive support systems to improve the resilience and psychological health of those experiencing ambiguous loss. Effective coping strategies include seeking social support, engaging in meaning-making activities, and using therapeutic interventions like resilience training and narrative therapy to improve the psychological health of those experiencing ambiguous loss. Healthcare providers should integrate narrative therapy and resilience training techniques, while social workers should enhance support systems involving community networks. Further research is urgently advocated to expand the understanding of ambiguous loss across various contexts and cultures, leading to more effective, tailored interventions. The study's contributions are significant, as it elucidates the complex dynamics of ambiguous loss and identifies effective coping mechanisms and therapeutic interventions. By highlighting how ambiguous loss differs from other losses in closure and resolution, the paper offers new insights into the tailored approaches necessary to support affected individuals. The study consolidates diverse aspects of ambiguous losses and makes unique suggestions for policy and practice in one scholarly work.