Editorial for the Special Issue “New Strategies in Cancer Pharmacotherapy: Development of Hormonal Antineoplastic Drugs, Cytotoxic Drugs and Targeted Therapies”

Martínez‐Campa, Carlos; Alonso‐González, Carolina

doi:10.3390/ijms21114081

Cited by 3 publications

References 13 publications

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Comparative effectiveness of Mirror Therapy and Music Therapy on psychomotor rehabilitation of ischemic stroke: A Systematic Review and Meta-Analysis

Estévez,

Pérez-Nieto,

Herrero

2024

Preprint

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The blockage of cerebral vessels is one of the most common strokes. The consequences may vary according to the location of the lesion, but psychomotor abilities are usually affected. Together with specific neurorehabilitation programs and pharmacological treatments some novel non-pharmacological therapies are emerging in recent years. In this context, the impact of both Mirror and Music therapies has been separately analyzed in different studies. However, it is not clear at a what point their true effects are similar or not. The main aim of this study was to carry out a systematic review and meta-analysis to analyze the effects of MiT and MuT over matched controls on the psychomotor recovery of ischemic stroke patients as well as to explore whether the benefits of one of them may outpace the other by using network meta-analytical technics. A total of 28 observations (Mirror therapy, N = 15; Music therapy, N = 13), from 11 randomized trials’ studies we included in the network approach analysis which includes both direct and indirect comparisons. The systematic review revealed interesting similarities in the implementation of the therapies. The results of the meta- analysis showed small to moderate significant effect sizes of both Mirror and Music therapies over paired controls and non-significant differences between them.

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Comparative effectiveness of Mirror Therapy and Music Therapy on psychomotor rehabilitation of ischemic stroke: A Systematic Review and Meta-Analysis

Estévez,

Pérez-Nieto,

Herrero

2024

Preprint

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Effects of Iron on Efficacy of Photodynamic Therapy Using Photolon in a Mouse Model of CT26 Colon Cancer

2023

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Pharmacological Activity of LHT-17-19 in Cultures of Egfr-Expressing Epithelial Tumors

M.Yu.

Тумутолова

Deryabina

et al. 2022

Vestnik "Biomedicina i sociologiya"

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Abstract. . In the study, the pharmacological activity of the pyridine derivative LHT-17-19 was studied in relation to the culture of pancreatic cancer cells PANC-1 and the culture of bladder cancer cells HT-29 expressing the epidermal growth factor receptor. The cultures were obtained from the library of tumor strains of the Moscow Research Institute of Oncology. P.A. Herzen - a separate structural subdivision of the Federal State Budgetary Institution "NMITs Radiology" of the Ministry of Health of Russia. LHT-17-19 was synthesized in the Department of Chemistry, Technology of Synthetic Medicines and Analytical Control of JSC VNTs BAV (Russia). LHT-17-19 and the reference drug "Doxorubicin" 50 mg each were added to the cultivation medium in the concentration range from 10-8 to 10-v. Compounds LHT-17-19 were shown to be able to induce death and suppress the growth of pancreatic cancer squamous culture (PANC-1) and bladder (HT-29) tumor cells expressing EGFR over a wide range of concentrations. So for pancreatic cancer (PANC-1), the effective inhibitory concentration for the compound LHT-17-19 was 1.3 × 10-7 M, while for the reference substance doxorubicin it was 6.0 × 10-5 M. bubble (NT-29) - 2.4 × 10-7 M and 5.2 × 10-4 M, respectively.

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Editorial for the Special Issue “New Strategies in Cancer Pharmacotherapy: Development of Hormonal Antineoplastic Drugs, Cytotoxic Drugs and Targeted Therapies”

Cited by 3 publications

References 13 publications

Comparative effectiveness of Mirror Therapy and Music Therapy on psychomotor rehabilitation of ischemic stroke: A Systematic Review and Meta-Analysis

Comparative effectiveness of Mirror Therapy and Music Therapy on psychomotor rehabilitation of ischemic stroke: A Systematic Review and Meta-Analysis

Effects of Iron on Efficacy of Photodynamic Therapy Using Photolon in a Mouse Model of CT26 Colon Cancer

Pharmacological Activity of LHT-17-19 in Cultures of Egfr-Expressing Epithelial Tumors

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