“…Since the past four years of the special issues of this month, the Novel Therapeutic Approaches in Nephrology and Hypertension of the Current Opinion in Nephrology and Hypertension [3][4][5][6], a variety of clinical and research topics have been discussed from the scientific and epidemiology through clinical and policy perspectives related to various interventions or 'what we can do' for kidney diseases and transplantation, in this year's current special collection, apart from the interventions, methods or 'how we can implement' is emphasized to successfully translate scientific knowledge to real-world clinical practice.…”