Editorial: Medicinal Chemistry Research in India

Vishwakarma, Ram A.

doi:10.1021/acsmedchemlett.7b00064

Cited by 2 publications

(3 citation statements)

References 20 publications

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“…One would also imagine that India’s academic and industrial sectors are brimming with specialized workers in organic synthesis and medicinal chemistry research toward drug discovery efforts, given its recognized significance in global drug security. An editorial published in ACS Medicinal Chemistry Letters in 2017 provided insights about medicinal chemistry research in India over the span of two years (2015–2016) . It indicated that, after aligning with the international patent regime in 2005, medicinal chemistry research in India got a boost and, as a result, several research groups from both academia and industries had emerged.…”

Section: Pharmacy Of the Worldmentioning

confidence: 99%

Catalyzing the Future of Medicinal Chemistry Research in India

Talukdar

Sarkar

2023

J. Med. Chem.

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The present publication provides a comprehensive look at more than a decade (2010 to midyear of 2023) of medicinal chemistry research in India, focusing on contributions to medicinal chemistry and drug discovery from both Indian academia and industries. The work provides an overview of cutting-edge medicinal chemistry research along with the organictransformation-based chemical research scenarios in India in the past decade. It also distinguishes areas of research as well as contributions from different federal research institutes, state universities, central universities, and private universities by their geographical locations around India. The paper takes broader stock of the situation by comparing the articles published in the two internationally acclaimed journals in the field, viz. Journal of Medicinal Chemistry and Organic Letters, which highlights the current research trends as well as the thrust needed at the grass-roots level to boost medicinal chemistry and drug discovery research in India. Finally, we believe that this discussion may create a pathway for policymakers and funding agencies to focus their efforts to motivate lesser inclined institutions as well as provide incentives to the institutions primarily involved in medicinal chemistry research, as they already have built capacity for such research.

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Section: Pharmacy Of the Worldmentioning

confidence: 99%

Catalyzing the Future of Medicinal Chemistry Research in India

Talukdar

Sarkar

2023

J. Med. Chem.

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“…Other authors have analyzed its socioeconomic impact and public policy implications and recommendations,11, 12, 13, 14, 15 drug development in India and in comparison with other emerging countries,16, 17 drug discovery in private companies and in publicly funded institutions,18, 19 current changes and opportunities,20, 21 or out‐licensing deals 22. We recently reviewed contract and collaborative research alliances between Indian and global pharmaceutical companies 23.…”

Section: Introductionmentioning

confidence: 99%

“…Drug discovery and pharmaceutical R&D in India has been reviewed and analyzed previously,b ut generally from specific points of view,s uch as its historical background, [6][7][8] the fate of the big pharma companies, [5,9] or the impact of process versus product patent output as ac onsequence of the Agreement on Trade-Related Aspects of Intellectual Property Rights( the socalled TRIPS agreement). [10] Other authors have analyzed its so-cioeconomic impact and public policy implicationsa nd recommendations, [11][12][13][14][15] drug development in India and in comparison with other emerging countries, [16,17] drug discovery in private companies and in publiclyf unded institutions, [18,19] current changes ando pportunities, [20,21] or out-licensing deals. [22] We recently reviewed contract and collaborative research alliances between Indiana nd globalp harmaceutical companies.…”

Section: Introductionmentioning

confidence: 99%

The Drug Discovery and Development Industry in India—Two Decades of Proprietary Small‐Molecule R&D

Differding¹

2017

ChemMedChem

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This review provides a comprehensive survey of proprietary drug discovery and development efforts performed by Indian companies between 1994 and mid‐2016. It is based on the identification and detailed analysis of pharmaceutical, biotechnology, and contract research companies active in proprietary new chemical entity (NCE) research and development (R&D) in India. Information on preclinical and clinical development compounds was collected by company, therapeutic indication, mode of action, target class, and development status. The analysis focuses on the overall pipeline and its evolution over two decades, contributions by type of company, therapeutic focus, attrition rates, and contribution to Western pharmaceutical pipelines through licensing agreements. This comprehensive analysis is the first of its kind, and, in our view, represents a significant contribution to the understanding of the current state of the drug discovery and development industry in India.

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Editorial: Medicinal Chemistry Research in India

Cited by 2 publications

References 20 publications

Catalyzing the Future of Medicinal Chemistry Research in India

Catalyzing the Future of Medicinal Chemistry Research in India

The Drug Discovery and Development Industry in India—Two Decades of Proprietary Small‐Molecule R&D

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