Editorial: metabolomic biomarkers for colorectal adenocarcinoma and in the differentiation between irritable bowel syndrome and ulcerative colitis in clinical remission — confounded by the gut microbiome? Authors' reply

Bond, Ashley; Probert, Chris

doi:10.1111/apt.15196

Cited by 1 publication

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“…However, this medicine can help dampness and choke qi, so it should be used with caution for patients with spleen deficiency and internal stagnation of dampness [ 34 ]. The main acupoints are Shenque, Tianshu, Daheng, Qihai, Guanyuan, Zhongji, Zhongwan, Xiawan, Shui, and other acupoints [ 35 , 36 ]. Cross moxibustion connects Ren meridian, Dai pulse, foot Yangming stomach meridian, foot Taiyin spleen meridian, foot Jueyin liver meridian, foot Shaoyin kidney meridian, and other eight and twelve meridians.…”

Section: Discussionmentioning

confidence: 99%

Effect of Shugan Jianpi Recipe Combined with Cross Moxibustion on Biochemical Examination Indexes and Total Score of TCM Symptoms in Patients with Spleen-Stomach Damp-Heat Diarrhea Irritable Bowel Syndrome

Liu

Ruan²,

Tong³

et al. 2022

Computational and Mathematical Methods in Medicine

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Objective. To explore the effect of Shugan Jianpi recipe combined with cross moxibustion on biochemical examination indexes and total score of TCM symptoms in patients with spleen-stomach damp-heat diarrhea irritable bowel syndrome (IBS). Methods. Sixty patients with spleen-stomach damp-heat diarrhea (IBS) treated in our hospital from January 2019 to September 2021 were enrolled. The patients were randomly assigned into the control group and study group. The control group was treated with Chang Shugan Jianpi recipe, and the study group was treated with Shugan Jianpi recipe combined with cross moxibustion. The curative effect, single symptom score, total score of TCM clinical symptoms, plasma gastrointestinal hormone level, IBS-QOL score, and recurrence were compared. Results. First of all, we compared the curative effects. The study group was significantly effective in 24 cases, effective in 5 cases, and ineffective in 1 case, and the effective rate was 96.67%. In the control group, 13 cases were markedly effective, 10 cases were effective, and 7 cases were ineffective, and the effective rate was 76.67%. The effective rate of the study group was higher compared to the control group ( P < 0.05 ). Secondly, the individual symptom scores were compared. Compared between the two groups, the scores of diarrhea times, stool characteristics, abdominal pain, and abdominal distension in the study group were lower compared to the control group ( P < 0.05 ). After treatment, the total score of TCM clinical symptoms decreased. Compared between the two groups, the total score of TCM clinical symptoms in the study group was lower compared to the control group at 1 week, 2 weeks, and 4 weeks after treatment ( P < 0.05 ). After treatment, the levels of 5-HT and VIP decreased. The levels of 5-HT and VIP in the study group were lower compared to the control group ( P < 0.05 ). The scores of anxieties, health worry, behavioral disorder, social reaction, somatic intention, interpersonal relationship, dietary concern, and sexual behavior in the study group were lower compared to the control group. The IBS-QOL scores were significantly lower compared to the control group ( P < 0.05 ). Finally, we compared the recurrence. The recurrence rate in the study group was lower compared to the control group ( P < 0.05 ). Conclusion. The prescription combined with cross moxibustion has the effect of soothing the liver and invigorating the spleen, resolving dampness and stomach, and can reduce the main clinical symptoms of patients with diarrhea IBS of spleen-stomach damp-heat type, and the overall effect is significant. It can also enhance the emotional state of anxiety and depression and achieve the overall psychological and physical balance and health state, and the recurrence rate is low, which can be further applied in clinic.

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Section: Discussionmentioning

confidence: 99%

Effect of Shugan Jianpi Recipe Combined with Cross Moxibustion on Biochemical Examination Indexes and Total Score of TCM Symptoms in Patients with Spleen-Stomach Damp-Heat Diarrhea Irritable Bowel Syndrome

Liu

Ruan²,

Tong³

et al. 2022

Computational and Mathematical Methods in Medicine

View full text Add to dashboard Cite

show abstract

Editorial: metabolomic biomarkers for colorectal adenocarcinoma and in the differentiation between irritable bowel syndrome and ulcerative colitis in clinical remission — confounded by the gut microbiome? Authors' reply

Abstract: Linked ContentThis article is linked to Keshteli et al and Leong et al papers. To view these articles, visit https://doi.org/10.1111/apt.15140, and https://doi.org/10.1111/apt.15171.

Cited by 1 publication

References 5 publications

Effect of Shugan Jianpi Recipe Combined with Cross Moxibustion on Biochemical Examination Indexes and Total Score of TCM Symptoms in Patients with Spleen-Stomach Damp-Heat Diarrhea Irritable Bowel Syndrome

Effect of Shugan Jianpi Recipe Combined with Cross Moxibustion on Biochemical Examination Indexes and Total Score of TCM Symptoms in Patients with Spleen-Stomach Damp-Heat Diarrhea Irritable Bowel Syndrome

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