EDTA and urea peroxide for root canal preparation

Stewart, George G.; Kapsimalas, Peter; Rappaport, Harold M.

doi:10.14219/jada.archive.1969.0114

Cited by 62 publications

(29 citation statements)

References 11 publications

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“…The origin of paste-type preparations dates back to 1961, when Stewart devised a combination of urea peroxide with glycerol (138). Later, based on the results of that first preliminary study and the successful introduction of EDTA to endodontic practice (129), urea peroxide and EDTA were combined in a water-soluble carbowax (polyethylene glycol) vehicle (139). This product has since been commercially available.…”

Section: Chelator Solutionsmentioning

confidence: 99%

Root Canal Irrigants

Zehnder

2006

Journal of Endodontics

1,579

1,508

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Section: Chelator Solutionsmentioning

confidence: 99%

Root Canal Irrigants

Zehnder

2006

Journal of Endodontics

1,579

1,508

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“…Early studies in which no antiseptic irrigants were used reported that 20 to 30 per cent of the root canals that were infected at the beginning of treatment yielded negative cultures at the end of the first appointment. [103][104][105] These studies are of limited value because they were performed with bacteriological techniques unsuited to the recovery of anaerobes.…”

Section: Antimicrobial Efficacy Of Manual Instrumentationmentioning

confidence: 99%

A big role for the very small—understanding the endodontic microbial flora

Figdor

Sundqvist

2007

Australian Dental Journal

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Apical periodontitis, an inflammatory process around the apex of a tooth root, is primarily a sequel to microbial infection of the pulp space. The microbial flora is composed of a restricted group of the total oral flora, selected by environmental pressures of anaerobiosis, nutrition and competition with other species and inhabits the root canal as a biofilm of coaggregated communities in an extracellular matrix. The untreated infected canal is generally composed of a polymicrobial mix with approximately equal proportions of Gram-positive and Gram-negative species, dominated by obligate anaerobes. The type of microbial flora in the root-filled tooth with persistent apical periodontitis has very different characteristics. These infections are characterized by one or just a few species, predominantly Grampositive micro-organisms with an equal distribution of facultative and obligate anaerobes. Enterococcus faecalis has been a conspicuous finding in most studies. Because the primary aetiological problem is infection, endodontic treatment is directed at control and elimination of the root canal flora by working in a sterile way. Based on current knowledge, the best available method for obtaining clean, microbe-free root canals is by instrumentation with antimicrobial irrigation reinforced by an intracanal dressing with calcium hydroxide.Key words: Root canal flora, ecological niche, antibacterial treatment, root canal preparation, root canal irrigants.Abbreviations and acronyms: EDTA = ethylenediamine tetra-acetic acid; FTM = fluid thioglycolate medium; NaOCI = sodium hypochlorite solution; SEM = scanning electron microscope.

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“…The study of this permeability is very important because root canal therapy is performed with the association of instrumentation and irrigating solutions, which penetrate into these canaliculli, remove debris, and smear layer, easing and improving the final sealing [1][2][3][4][5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%