The Himalayan country of Nepal is vulnerable to landslides, earthquakes, and fires. Its inhabitants need to be empowered on how to react in emergencies to prevent fatalities and respond to crises efficiently while promoting longer-term sustainability and resilience. This research project, a collaborative effort involving teachers, students, and researchers, highlights the design and implementation of games for disaster risk reduction tested in remote schools. Three interactive games were developed using an iterative game design process and testing in workshops aiming to ensure the inclusivity and diversity of the project. The games targeted preparedness and response to landslides, earthquakes, and house fires. The outcome has proven that the game-based approach to teaching and learning is crucial in empowering underserved school children often left out in formal and informal disaster management processes. This study has shown that game-based learning of disaster preparedness and response effectively empowers resource-deficient communities and regions of the Global South.