EEG Monitoring during Therapeutic Hypothermia in Neonates, Children, and Adults

Abend, Nicholas S.; Mani, Ram S.; Tschuda, Tammy N.; Chang, Tae Young; Topjian, Alexis; Donnelly, Maureen; LaFalce, Denise; Krauss, Margaret C.; Schmitt, Sarah; Levine, Joshua M.

doi:10.1080/1086508x.2011.11079816

Cited by 26 publications

(12 citation statements)

References 124 publications

(158 reference statements)

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“…Although children treated with hypothermia in our cohort were statistically more likely to have a poor outcome, this likely reflects the severity of illness and not EEG related findings. The use of therapeutic hypothermia following cardiac arrest has been shown not to improve outcomes in children (35) and adults (36) and EEG findings modulated by moderate hypothermia are likely minimal (37). Thus, the heterogeneity of temperature in this cohort is unlikely to have significantly influenced the data collection or outcomes.…”

Section: Discussionmentioning

confidence: 99%

Early Electroencephalographic Findings Correlate With Neurologic Outcome in Children Following Cardiac Arrest

Ostendorf

Hartman

Friess

2016

Pediatric Critical Care Medicine

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Objective To determine the clinical and electroencephalographic findings associated with prognosis in non-neonate children following cardiac arrest. Design Retrospective observational study. Setting Pediatric Intensive Care Unit and Cardiac Intensive Care Unit. Patients Non-neonate children with a history of cardiac arrest > 2 minutes and EEG monitoring within 72 hours of return of spontaneous circulation. Measurements and Main Results Clinical and features, neurophysiological data and Pediatric Cerebral Performance Category (PCPC) scores were collected. EEG traces were reviewed in a blinded manner, all seizures and EEG findings noted, and the EEG was scored at 1 hour, 24 hours and CEEG end. Discrete data regarding specific characteristics of the EEG background and seizures were studied. Univariate and multivariate analyses were performed to identify associations between clinical variables, EEG findings and PCPC score at hospital discharge. Multivariate analysis of 73 children revealed duration of cardiac arrest < 20 minutes or continuous EEG background activity within 12 hours post-ROSC were associated with good short term neurological outcome. Change in EEG background score over time and EEG data collected after the initial hour were not associated with outcome. Conclusions Following pediatric cardiac arrest, an initially normal EEG or generalized slowing of the EEG background was associated with good neurologic outcome at hospital discharge.

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Section: Discussionmentioning

confidence: 99%

Early Electroencephalographic Findings Correlate With Neurologic Outcome in Children Following Cardiac Arrest

Ostendorf

Hartman

Friess

2016

Pediatric Critical Care Medicine

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“…Neurological examination revealed no response to verbal and tactile stimulation; additionally, unconsciousness and myoclonic seizures were observed. Spasticity of all the extremities was also observed and the diagnosis of HIE was confirmed according to clinical, physical examination findings and EEG4 5 which confirms HIE with severe bioelectrical impairment in both the hemispheres. She received Valproat treatment because of seizure activity in left centrofrontal region for 6 months.…”

Section: Case Presentationmentioning

confidence: 64%

The role of positron emission tomography/CT in hypoxic ischaemic encephalopathy in children

et al. 2013

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“…ous seizure pattern for ≥ 30 minutes, presenting as a "saw tooth pattern" or as continuous increases of the lower and upper margins [14].…”

Section: Discussionmentioning

confidence: 99%

Correlation of Amplitude-Integrated Electroencephalogram (aEEG) and Early Neurological Outcome in Newborn Treated with Therapeutic Hypothermia for Hypoxic Ischemic Encephalopathy (HIE): An Audit

Ananthan¹,

Nanavati²,

Shivamallappa³

et al. 2019

Act Scie Paedia

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Amplitude-integrated electroencephalogram (aEEG) is a commonly used monitoring tool for assessing cortical electrical activity and can also detect seizures. • aEEG monitoring in infants with moderate to severe HIE correlates significantly with short term neurological outcomes • The timely detection of short term neurological abnormalities with the aid of aEEG enables timely initiation of early intervention therapy. This may help to achieve better long term neurological outcome.

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EEG Monitoring during Therapeutic Hypothermia in Neonates, Children, and Adults

Cited by 26 publications

References 124 publications

Early Electroencephalographic Findings Correlate With Neurologic Outcome in Children Following Cardiac Arrest

Early Electroencephalographic Findings Correlate With Neurologic Outcome in Children Following Cardiac Arrest

The role of positron emission tomography/CT in hypoxic ischaemic encephalopathy in children

Correlation of Amplitude-Integrated Electroencephalogram (aEEG) and Early Neurological Outcome in Newborn Treated with Therapeutic Hypothermia for Hypoxic Ischemic Encephalopathy (HIE): An Audit

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