“…Anesthesia can suppress consciousness by simply interrupting binding and integration between local brain areas without the need for suppressing EEG activity (Alkire and Miller, 2005; Alkire et al, 2008). This is the reason why, in clinical practice, general anesthesia can be associated with almost normal EEG with peak activity in the alpha band (Facco et al, 1992), while in deep, irreversible coma, consciousness can be lost even with a preserved alpha pattern activity (Facco, 1999; Kaplan et al, 1999). In short, loss of consciousness can occur with preserved EEG activity, while, in the case of a flat EEG, neither cortical activity nor binding can occur; furthermore, short latency somatosensory-evoked potentials, which explore the conduction through brain stem up to the sensory cortex and are more resistant to ischemia than EEG, have been reported to disappear during cardiac arrest (Yang et al, 1997).…”