EEMCO guidance for the assessment of skin topography

Levêque, J. L.

doi:10.1016/s0926-9959(98)00094-4

Cited by 58 publications

(69 citation statements)

References 29 publications

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“…The skin surface topography was assessed on skin casts according to the EEMCO recommendations [31]. Optical profilometry was performed by recording the shadows created by oblique lightning (fig.…”

Section: Methodsmentioning

confidence: 99%

A Pilot Study on Seborrheic Dermatitis Using Pramiconazole as a Potent Oral Anti-<i>Malassezia</i> Agent

Pierard

Ausma²,

Henry

et al. 2007

Dermatology

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Background: Seborrheic dermatitis is considered to be a Malassezia-driven disease. Little objective information is available so far from biometrological quantitative assessments of this skin condition. Pramiconazole is a novel triazole with potent in vitro antifungal activity, especially against Malassezia spp. Objective: To study the sequential effects of pramiconazole on Malassezia, inflammation and epidermal changes. Method:This study was performed in 2 groups of subjects suffering from seborrheic dermatitis. The first group (n = 17) remained untreated and was used as control. Clinical, mycological and biometrological assessments were performed at inclusion and during the following 2 weeks. The second group of subjects (n = 10) received a single 200-mg oral dose of pramiconazole at inclusion. Clinical, mycological and biometrological evaluations were performed before and during 1 month following the single antifungal intake. For both parts of the study, several parameters were assessed including yeast density, desquamation, erythema, itching and sebum excretion. Results: In the control group, no significant changes were observed in any of the parameters during the observation period. The findings were markedly different in the pramiconazole-treated subjects. The yeast density was significantly improved on days 3, 7 and 28. Desquamation, erythema, itching, and the global clinical evaluation as assessed by the patients and investigators became significantly improved on days 7 and 28. A trend in decrease of scaliness was noted. No effect on sebum excretion was evidenced. In conclusion, a single 200-mg dose of pramiconazole exhibitsin vivo efficacy in controlling some important clinical aspects of seborrheic dermatitis. Following a reduction in the number of yeasts on day 3, a decrease in the severity of clinical signs and symptoms occurred from day 7 onwards. Sebum excretion appeared uninvolved in the clearing process of seborrheic dermatitis. Conclusion: A single 200-mg dose of pramiconazole appears to abate seborrheic dermatitis. The density in Malassezia present on lesional skin is first decreased, followed by clearing of the clinical signs.

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Section: Methodsmentioning

confidence: 99%

A Pilot Study on Seborrheic Dermatitis Using Pramiconazole as a Potent Oral Anti-<i>Malassezia</i> Agent

Pierard

Ausma²,

Henry

et al. 2007

Dermatology

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“…Replicas used to collect information about the skin surface can be used in different ways to collect information about pores [14, 15, 16]. The most widely used material for skin replicas is silicone polymer, but one major pitfall is the presence of air bubbles in the replica, especially at the site of pores.…”

Section: Skin Relief Assessmentmentioning

confidence: 99%

The Conundrum of Skin Pores in Dermocosmetology

et al. 2005

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‘Skin pore’ is a term used by lay people and in the field of cosmetology. It remains misleading when it is not clearly defined. Indeed, lay people use it with at least 3 different meanings. Basically, invisible pores represent the openings of the sweat gland apparatus. By contrast, the visible pores represent enlarged empty funnel-shaped or cylindrical horny impacted openings of pilosebaceous follicles. This review describes some of the current objective methods used to describe skin pores.

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“…It has been clarified that wrinkles, a symptom of aging, are formed due to age-related changes in skin elasticity and the degeneration of dermal collagen and elastin, and ultraviolet light and cigarette smoking are involved factors [9] [10]. In photoaging induced by chronic exposure to ultraviolet light, induction of matrix metalloproteinases (MMPs) is enhanced, and accompanying degradation of extracellular matrix, such as collagen Types I and III and elastin, promotes wrinkle formation [11].…”

Section: Discussionmentioning

confidence: 99%

Efficacy Evaluation of Unique Skincare Product Containing Pseudo-Ceramide for Fine Wrinkles in Japanese Female Atopic Dermatitis Patients

Takahashi¹,

Mori²,

Nishizaka³

et al. 2014

JCDSA

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Background/Objective: Dryness is considered to be an early developmental mechanism of wrinkles, and fine line formation is marked in atopic dermatitis (AD) accompanied by dry skin. To evaluate the efficacy of a skincare product with a moisturizing effect increased by lamellar formulation of pseudo-ceramide for fine lines and wrinkles, a use test was performed applying the product to non-lesional dry skin in patients with atopic dermatitis. Method: The test product was an essence containing pseudo-ceramide formulated in a lamellar structure. The study design was a nine-week single-center non-comparative study, and the evaluation items were the grade of wrinkles at the corners of the eyes judged by a dermatologist, replica analysis, and instrumental measurement (skin surface moisture and transepidermal water loss). Results: Nine-week continuous use of the test product significantly improved the score of wrinkles at the corners of the eyes judged by a dermatologist and wrinkle area ratio on replica analysis of the corners of the eyes and cheeks, compared with those at study initiation. With this improvement, the losses of skin surface moisture and transepidermal water were also significantly improved. Conclusion: It was clarified that the tested pseudo-ceramide-formulated skincare product not only improved the barrier function for atopic dermatitis, but also exhibited an effect on fine lines and wrinkles of dry skin.

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EEMCO guidance for the assessment of skin topography

Cited by 58 publications

References 29 publications

A Pilot Study on Seborrheic Dermatitis Using Pramiconazole as a Potent Oral Anti-<i>Malassezia</i> Agent

A Pilot Study on Seborrheic Dermatitis Using Pramiconazole as a Potent Oral Anti-<i>Malassezia</i> Agent

The Conundrum of Skin Pores in Dermocosmetology

Efficacy Evaluation of Unique Skincare Product Containing Pseudo-Ceramide for Fine Wrinkles in Japanese Female Atopic Dermatitis Patients

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