This paper proposed an energy-efficient reconfigurable accelerator for keyword spotting (EERA-KWS) based on binary weight network (BWN) and fabricated in 28-nm CMOS technology. This keyword spotting system consists of two parts: the feature extraction based on melscale frequency cepstral coefficients (MFCC) and the keywords classification based on a BWN model, which is trained through the Google's Speech Commands database and deployed on our custom. To reduce the power consumption while maintaining the system recognition accuracy, we first optimize the MFCC implementation with approximate computing techniques, including Pre-emphasis coefficient transformation, rectangular Mel filtering, Framing and FFT optimization. Then, we propose a precision self-adaptive reconfigurable accelerator with digital-analog mixed approximate computing units to process the BWN efficiently. Based on the SNR prediction of background noise and post-detection of network output confidence, the BWN accelerator data path can be dynamically and adaptively reconfigured as 4, 8, or 16 bits. For the BWN accelerator, we proposed a time-delay based addition unit to process bit-wise approximate computing for the convolution layers and fully connected layers, and a LUT based unit for the activation layers. Implemented under TSMC 28 nm HPC+ process technology, the estimated power is 77.8 µW ∼ 115.9µW, the energy efficiency can achieve 163 TOPS/W, which is over 1.8× better than the state-of-the-art architecture.