Transit behaviour of solid and liquid digesta along the gastrointestinal tract is partially modulated by physicochemical properties (PP) of the diet. Understanding which dietary PP influence digesta transport is relevant for predicting nutrient absorption kinetics. In this study, we evaluated the potential of dietary PP for predicting mean retention time (MRT) of digesta, combining data from four experiments (21 diets, n=166 pigs, BW=42 ± 14.0 kg) including diets broadly ranging in PP. The MRT of digesta in various GIT segments, measured using similar methodology, was related to dietary PP, such as rheological parameters (extract viscosity and solid phase moduli plus linear viscoelastic (LVE) range) and water binding capacity (WBC). For each GIT segment and digesta phase, i.e. solids and liquids, PP were selected after a correlation and multicollinearity analysis, followed by MaxR and Stepwise variable selection methods. Subsequently, multiple regression analysis was performed, including selected PP as predictor variables. Mean retention time of solid (MRTsolid) and liquid (MRTliquid) digesta, and digesta phase segregation was predicted using the model equations with (1) selected PP (full model), (2) WBC only, and (3) extract viscosity only; and calculated vs. observed values were compared. Coefficients of determination (R 2 ) were used to select the best model to predict digesta MRT per segment. Dietary PP were in particular capable of predicting digesta phase segregation in the stomach (R 2 = 0.56), largely explained by WBC (R 2 = 0.51), and MRTliquid (R 2 = 0.26), explained by WBC and rheological parameters. Dietary PP were typically less well predicting MRT in the small and large intestine (R 2 = 0.07 -0.17), although phase segregation in the cecum was explained reasonably well (R 2 = 0.26). Full PP-models, including rheological parameters and WBC, better predicted digesta MRT of solids and liquids in all the segments than only considering dietary WBC or extract viscosity; whereas WBC was the most important predictor for phase segregation in the stomach. Extract viscosity explained negligible variation in MRT of solids, liquids, and digesta phase segregation. This information can be used in feed formulation to better anticipate how dietary physicochemical characteristics influence digestion kinetics.