Efeito Da Monensina Sódica Sobre O Perfil Metabólico De Ovelhas Antes E Após O Parto

Abstract

, 20 e 10 dias antes do parto, no momento do parto e nos 10, 20 e 30 dias pós-parto. As variáveis mensuradas foram: glicose, frutosamina, ácidos graxos não esterificados (AGNEs), β-hidroxibutirato, colesterol, triglicérides, proteína total, albumina, ureia e pesquisa de corpos cetônicos na urina. As determinações hormonais foram cortisol e a insulina. No fluido ruminal foi determinado o pH e a concentração dos ácidos graxos voláteis. Na análise estatística foi empregada a ANOVA e estudo de correlação (P<0,05). A monensina elevou (P<0,05) a concentração do propionato no rúmen e frutosamina e insulina no sangue. A administração da monensina promoveu melhora em alguns indicadores do balanço energético. Palavras-chave: ácidos graxos voláteis; ionóforo; ovinos; perfil energético; perfil proteico. AbstractThe study was carried out to analyze the effect of monensin supplementation during 60 days prior to parturition, and 30 days postpartum, on the metabolic and hormonal profile of ewes. Pregnant ewes (n=13) were randomly divided into two groups: monensin group (n = 7; 30 mg/day) and control group (n = 6). Blood and ruminal fluid samples were collected 60, 50,40,30,20 and 10 days prior to parturition, at the time of parturition and on 10, 20 and 30 days postpartum. The following variables were analyzed: glucose, fructosamine, non-esterfied fatty acids, β-hydroxybutyrate, cholesterol, triglycerides, total protein, albumin, urea and ketone bodies in the urine. The hormonal determinations were cortisol and insulin. The analysis of the ruminal fluid involved pH and concentration of volatile fatty acids. The statistical analysis involved ANOVA and correlation studies (P<0,05). Monensin increased (P<0,05) the propionic acid concentration in the rumen and blood fructosamine and insulin. The administration of monensin improved some indicators of energy balance.

Effects of Dietary Sodium Monensin on the Metabolic and Hormonal Profiles of Dairy Goats During the Peripartum Period

“…Analyzing the concentration of chloride ions in the rumen content, although the values were observed to have decreased overtime, no significant differences were observed between the different sampling periods or between the groups (p > 0.05) (Figure 3). The values obtained, 30.94 mmol/L in MG and 33.38 mmol/L in the CG, are slightly above the reference range for the species (21.0 ± 2.2 mmol/L) (5) . The importance of this data is precisely the difference between the parameters found in the international literature and the concentrations of this element in this study, that is, in healthy dairy goats living according to Brazilian environmental, climate, and food patterns.…”

“…sheep, obtained similar effects on the decrease of NEFAs during peripartum. However, Sadjadian et al (10) , who also worked with dairy goats, and Lima et al (5) , working with sheep, did not find relevant effects on the NEFAs values in the peripartum period when using monensin.…”

“…However, there were no differences between the groups (p > 0.05) (Figure 3). Brown and Hogue (13) and Aderinboye et al (15) working with goats, Markantonatos et al (16) working with dairy cows, and Lima et al (5) working with sheep also found no significant variations in pH between groups of animals receiving monensin supplementation or the control animals. This pH stability is probably attributed to the steady concentration of volatile fatty acids in the rumen during the experiment.…”

“…These factors explain the higher level of NEFAs at calving observed in both groups in this study. However, Rios et al (19) , working with dairy goats, and Lima et al (5) , in a study on monensin supplementation to the diet of sheep, observed an increase in the NEFAs in the initial lactation period and explained this result in terms of the high energy requirement for milk production during this period.…”

“…In addition, it was observed that these alterations lead to a more positive adaptive response during the transitional period and lactation (4) . Monensin supplementation in pregnant sheep during the transition period has shown positive effects on energy indicators and milk components (5,6) .…”