Efeito da solução de Ringer com lactato sobre os equilíbrios hidroeletrolítico e acidobase de equinos, ovelhas e bezerros sadios

Cosenza, Mariana; Pereira, Priscilla Fajardo Valente; Fernandes, Loraine Inês; Dearo, Antonio Cezar de Oliveira; Flaiban, Karina Keller Marques da Costa; Lisbôa, Júlio Augusto Naylor

doi:10.1590/s0103-84782013005000128

Cited by 12 publications

(12 citation statements)

References 8 publications

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“…In concentrations close to the upper limit in this study, hyperchloremia may not necessarily be related to pregnancy, since the mean values of Clin the empty ewes were also slightly above reference; therefore, it cannot be considered clinically significant. As in this study, Cosenza et al (2013) described the mean value of 116.46±1.88mmol/L chloride in healthy, but non-pregnant or lactating ewes. The chloride levels did not mean a pathological process, but could be linked to the mineral salt intake of the ewes during pregnancy (Souza et al 2016), which occurred ad libitum from the salt trough and was added to the feed.…”

Section: Resultssupporting

confidence: 57%

Comparison of electrolyte and acid-base balances of Dorper breed ewes between single and twin pregnancies

et al. 2019

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During pregnancy there are modifications in the metabolic profile of sheep that may predispose to the occurrence of metabolic disorders, of which pregnancy toxaemia (PT) is highlighted. Blood gas analysis is detects changes in acid-base and electrolyte balance effectively. The objectives of this study were to study the acid-base and electrolyte balance of sheep during gestation and in the immediate peripartum (up to 48 hours postpartum), comparing single gestation with twins. Sixty healthy sheep of Dorper breed, two to five years old were raised in a semi-intensive system and were divided in two experimental groups: Group 1: 30 ewes, with ultrasonographic diagnosis of single fetus gestation; Group 2: 30 ewes, with ultrasonographic diagnosis of twin pregnancy. The experimental moments were defined as: MI-immediately after artificial insemination (control); MG30 - 30 days of gestation; MG90 - 90 days of gestation; MG120 - 120 days of gestation; MG130 - 130 days of gestation; MG140 - 140 days of gestation; MP - lambing; MPP1 - 24h postpartum; MPP2 - 48h postpartum. At all times 1mL of blood was collected per jugular vein puncture for blood gas evaluation in a portable equipament (I-Stat®). The pH, carbon dioxide pressure (PCO2), bicarbonate (HCO3-), base excess (BE), sodium (Na+), potassium (K+), chloride (Cl-), ionized calcium (Ca+2), lactate, anion gap (AG) were mensured and strong ion difference (SID) were calculed. This work showed that there were changes in acid-base and electrolyte balance in pregnant ewes, due to the decrease in BE, HCO3-, TCO2 and increase of lactate and AG during gestation, but the pH remained normal and did not present any difference among moments in both groups. Comparing the groups, single-gestation ewes presented higher alkaline expenditure at delivery than twin-gestation, evidenced by lower levels of BE and HCO3-. Lower Na+ levels were observed in prepartum; drop in K+ values with advancing gestation; hyperchloremia and hypocalcemia during gestation according to the reference standards for species; decreased iCa+2 levels in the final third of gestation in both groups. It was concluded that the ewes of this study were healthy until the last moment analyzed (48h postpartum), although have shown greater consumption of the alkaline reserve in the peripartum, being more explicit in the single gestation animals. In addition, this situation can be physiological and result in increased energy demand during gestation, more exacerbated by peripartum.

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Section: Resultssupporting

confidence: 57%

Comparison of electrolyte and acid-base balances of Dorper breed ewes between single and twin pregnancies

et al. 2019

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“…A concentração de Cl -, por outro lado, é menor do que a do plasma devido ao fato de a solução L84 possuir concentração de lactato maior do que a da SRL. Enquanto a administração da SRL não provoca desequilíbrios eletrolíticos e ácido-base iatrogênicos (Cosenza et al, 2013), justamente por ser balanceada, a administração da solução L84 determina redução da cloremia (Flaiban, 2010;Junqueira et al, 2015;Pereira, 2016), e isso deve ser entendido como o efeito iatrogênico primário mais importante. Aplicando-se os princípios da teoria dos íons fortes para a interpretação do equilíbrio ácido-base, o efeito alcalinizante da solução L84 ocorre consequentemente à redução da cloremia, o que aumenta a SID plasmática (Constable, 2014).…”

Section: Resultsunclassified

A velocidade de infusão da solução poli-iônica intravenosa contendo 84mEq/L de lactato determina a intensidade do efeito alcalinizante em equinos

Pinto

Bregadioli

Carvalho

et al. 2018

Arq. Bras. Med. Vet. Zootec.

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RESUMO O objetivo deste trabalho foi verificar os efeitos da solução poli-iônica intravenosa contendo 84mEq/L de lactato (L84) sobre os equilíbrios hidroeletrolítico e ácido-base de equinos, quando administrada de forma rápida ou lenta. Cinco equinos sadios adultos receberam a infusão contínua intravenosa da L84, em volume correspondente a 10% do peso corporal, em duas ocasiões: a) infusão rápida (16,66mL/kg/h) durante seis horas; b) infusão lenta (8,33mL/kg/h) durante 12 horas. Amostras de sangue venoso foram colhidas ao início da infusão (hora zero) e três, seis, nove, 12 e 24 horas após, e amostras de urina nas horas zero, seis, 12 e 24. Determinaram-se pH (sanguíneo e urinário), pCO2, HCO3 -, BE, PPT, lactato L, Na+, K+, Cl-, AG, SID, Atot, VVP, densidade urinária e excreções fracionadas urinárias de lactato L, Na+, K+ e Cl-. A L84 provoca efeito alcalinizante iatrogênico de menor magnitude quando administrada de forma lenta, porque os mecanismos renais, atuantes durante o período de infusão, promovem a correção gradativa do desequilíbrio. Pode-se concluir que a infusão de forma lenta da solução L84 em equinos é recomendável nos casos em que se suspeite de acidose metabólica e não seja possível quantificar o grau do desequilíbrio.

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“…Lactated Ringer's solution is a balanced, polyionic, crystalloid solution indicated for the simultaneous correction of dehydration and metabolic acidosis . Due to a relatively low concentration of lactate, the alkalising effect of lactated Ringer's solution has been shown to be reduced or absent in calves, sheep and healthy horses , and the inability of lactated Ringer's solution to correct experimentally induced metabolic acidosis was demonstrated in steers , ewes and calves .…”

Section: Introductionmentioning

confidence: 99%

Intravenous administration of a polyionic solution containing 84 mEq/l of lactate resolves experimentally induced hyperchloraemic acidosis in horses

Romão

Pereira

Flaiban

et al. 2015

Equine Veterinary Journal

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Efeito da solução de Ringer com lactato sobre os equilíbrios hidroeletrolítico e acidobase de equinos, ovelhas e bezerros sadios

Cited by 12 publications

References 8 publications

Comparison of electrolyte and acid-base balances of Dorper breed ewes between single and twin pregnancies

Comparison of electrolyte and acid-base balances of Dorper breed ewes between single and twin pregnancies

A velocidade de infusão da solução poli-iônica intravenosa contendo 84mEq/L de lactato determina a intensidade do efeito alcalinizante em equinos

Intravenous administration of a polyionic solution containing 84 mEq/l of lactate resolves experimentally induced hyperchloraemic acidosis in horses

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