Efek Suplementasi Virgin Coconut Oil Terhadap Parameter Metabolik Dan Antropometrik Tikus Wistar Jantan Obesitas

Wijaya, Hendy; Surdijati, Siti

doi:10.14710/jnc.v9i1.25324

Cited by 3 publications

(3 citation statements)

References 18 publications

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“…Ahn et al [ 42 ] proposed that fibre reduces the activity of digestive enzymes and the level of food penetration, supported by their finding that consumption of rice analogues with a fibre content of up to 22.1% significantly lowered blood sugar levels in diabetic rats (Δ 175 mg/dL). Furthermore, the addition of VCO to corn cookies has been shown to aid in the reduction in blood sugar levels in mice, while, similarly, [ 48 ] stated that the feeding of VCO lowered blood sugar levels in rats.…”

Section: Resultsmentioning

confidence: 99%

Blood Sugar, Haemoglobin and Malondialdehyde Levels in Diabetic White Rats Fed a Diet of Corn Flour Cookies

Aini

Sustriawan

Wahyuningsih

et al. 2022

Foods

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The purpose of the study was to analyse the chemical composition of corn cookies containing different types of sugar and fat, and determine their effect on physiological parameters in diabetic rats. The experimental animals were studied using a randomised block design with seven groups of rats. The test groups were as follows: group 1, negative control rats (normal) fed standard; group 2, positive control rats (diabetic) fed standard; group 3, diabetic rats fed wheat cookies; group 4, diabetic rats fed C1 corn cookies; group 5, diabetic rats fed C2 corn cookies; group 6, diabetic rats fed C3 corn cookies; and group 7, diabetic rats fed C4 corn cookies. The tests on the rats revealed that the cookies had significant effects on blood sugar, malondialdehyde (MDA) and haemoglobin levels as well as body weight parameters. Corn cookies containing crystalline coconut sugar and virgin coconut oil (VCO) were effective at lowering blood sugar and MDA levels while increasing haemoglobin and body weight in diabetic rats. Significantly, after four weeks on this diet, rats with diabetes mellitus were in the same overall condition as normal rats. These findings suggest that these cookies may be gluten-free functional foods suitable for diabetics. These findings suggest that diabetics can safely consume maize cookies.

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Section: Resultsmentioning

confidence: 99%

Blood Sugar, Haemoglobin and Malondialdehyde Levels in Diabetic White Rats Fed a Diet of Corn Flour Cookies

Aini

Sustriawan

Wahyuningsih

et al. 2022

Foods

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“…Jeringau (Acorus calamus) is a rhizome plant that is widely used as a traditional medicine for infectious diseases caused by bacteria or fungi (Wijaya & Surdijati, 2020). Its ability as an antimicrobial is due to the presence of phenolic compounds, flavonoids, alkaloids, terpenes, and tannins in the jeringau (Barua et al, 2014).…”

Section: Secondary Metabolite Induction Of Lipase Inhibitors By Fermentationmentioning

confidence: 99%

“…This is done because plants have a strong cell wall. In the presence of cell destruction by these microorganisms, secondary metabolites are expected to be released maximally (Wijaya & Surdijati, 2020). The fermentation process in plants can cause phenol levels to increase (Sulasiyah et al, 2018).…”

Section: Secondary Metabolite Induction Of Lipase Inhibitors By Fermentationmentioning

confidence: 99%

Fat-Rich Food Review on Obesity Control through Induction Enzyme Inhibitors

Sari

Afra

Sembiring

et al. 2021

BES

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Background: Obesity is an imbalance between height and weight due to excessive body fat tissue. The purpose of writing this review is to find out the effect of enzyme inhibitor induction on fat-rich foods as control of obesity. Method: Writing and assessing source problems related to using literature study methods. Results: One way of controlling obesity is by regulating dietary patterns and consumption of lipase inhibitors. Inhibition of lipase is one of the most widely developed effective ways in diet medicine. Inhibitory compounds cause pancreatic lipase to lose its ability in decomposition that enters the blood. The potency of plant-origin lipase inhibitor compounds can be increased in both number and performance. Increasing the production of secondary metabolite group inhibitors is by fermentation of microorganisms. Conclusion: Inhibition of triglyceride hydrolysis through inhibition of lipase enzymes can decrease and prevent obesity. Secondary metabolite induction can be fermented with microorganisms. The production of secondary metabolite compounds in medicinal plants can be increased in the presence of fermentation. Flavonoids can decrease the accumulation of lipids in the heart, reduce glucose absorption, inhibit the breakdown of polysaccharides into monosaccharides.

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A Systematic Review of Butterfly Pea Flowers (Clitoria ternatea L.) in Reducing Body Weight and Improving Lipid Profile in Rodents with Obesity

Utami,

Indarto,

Listyawati

et al. 2023

AMNT

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Background: Butterfly pea flowers (Clitoria ternatea L.) are edible plants found in Asian countries that have several phytochemical compounds thathave potential anti-obesity and anti-dyslipidemia. From several in vivo studies, the administration of various extracts of butterfly pea flowers has different effects to reduce body weight (BW) or body mass index (BMI), and lipid profiles. Objectives: To analyze systematically the effects of butterfly pea flowers on BW or BMI and lipid profiles in rodents with or without obesity. Methods: This study used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and bias risk using the Systematic Review Centre for Laboratory Animal Experimentation (SyRCLEs).Original articles were from Google Scholar, PubMed, ResearchGate, and Science-Direct with criteria: randomized control trial (RCT), published from 2019 to 2023, rodents, and research outcomes (BW and lipid profiles). Results: Four original articles met the research criteria. Giving 1,000 mg/kg BW of the aqueous extract of butterfly pea flower for seven days reduced BW. Another study reported that giving 130 mg/kg BW butterfly pea flowers kombucha inhibited weight gain. Doses of 0.25 and 0.50% of the aqueous extracts of butterfly pea flowers for 15 weeks did not affect BW butthe dose of 2% prevented weight gain. Conclusions: Butterfly pea flowers have beneficial effects on reducing BW and improving lipid profiles in rodents with severaldiets although vary in animal models, diet types, extraction methods, and research design. This study becomes important evidence for further study.

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Efek Suplementasi Virgin Coconut Oil Terhadap Parameter Metabolik Dan Antropometrik Tikus Wistar Jantan Obesitas

Cited by 3 publications

References 18 publications

Blood Sugar, Haemoglobin and Malondialdehyde Levels in Diabetic White Rats Fed a Diet of Corn Flour Cookies

Blood Sugar, Haemoglobin and Malondialdehyde Levels in Diabetic White Rats Fed a Diet of Corn Flour Cookies

Fat-Rich Food Review on Obesity Control through Induction Enzyme Inhibitors

A Systematic Review of Butterfly Pea Flowers (Clitoria ternatea L.) in Reducing Body Weight and Improving Lipid Profile in Rodents with Obesity

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