2021
DOI: 10.15562/ism.v12i2.956
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Efektivitas terapi inhibitor janus kinase pada vitiligo: tinjauan pustaka

Abstract: Background:Vitiligo is an autoimmune disease that causes progressive skin melanocyte destruction, clinically seen as asymptomatic depigmentation macule and poliosis. CD8+ T cell is the primary effector of melanocyte destruction, and the activities of CD8+ T cell are driven by interferon-γ (IFN-γ). The current vitiligo treatment options are often not satisfied with many limitations and a high recurrence rate. Janus Kinase (JAK) inhibitor is one of the emerging vitiligo therapies which has a more specific target… Show more

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