Effect assessment of laparoscopy in combination with traditional Chinese medicine decoction in the treatment of endometriosis

Abstract

Background: Endometriosis (EMs) affects about 10% of women of childbearing age. It is defined as functional endometrial tissue appearing in other parts of the uterine cavity, manifested by varying degrees of pelvic pain and pelvic mass, etc. Therefore, to improve the therapeutic effect of endometriosis, we must constantly explore new ways to treat the disease. The purpose of this study is to evaluate the effectiveness and safety of the combined use of laparoscopy and traditional Chinese medicine in the treatment of patients with EMs.Methods: A systematic literature search will be conducted at China National Knowledge Infrastructure, WanFang databases, VIP, SinoMed, PubMed, Embase, Web of Science, and the Cochrane library. The search period limit is from the time the date of database establishment to June 21, 2021. To ensure the comprehensiveness of the search, relevant references and conference literature are also included. The risk of bias in the final included studies will be evaluated based on the guidelines of the Cochrane Handbook for Systematic Reviews of Interventions. The RevMan software will be employed to perform data synthesis and statistical analysis.Results: The effectiveness and safety of laparoscopic surgery combined with traditional Chinese medicine decoction in the treatment of patients with EMs will be systematically evaluated. Conclusion:The results of this study will provide strong evidence for judging whether laparoscopy combined with traditional Chinese medicine decoction is an effective strategy for the treatment of patients with EMs.

Research Progress in Conservative Treatment of Osteoarthritis in Traditional Chinese and Western Medicine

“…Studies have found that acupuncture has a significant inhibitory effect on the expression of inflammatory factors, thereby protecting joint cartilage, improving local microenvironment, effectively alleviating arthritis symptoms, and improving patient signs [42] . Traditional Chinese medicine believes that "if you do not pass, it is pain", Tuina has the effects of channeling meridians, regulating muscles and bones, removing blood stasis, etc., in the process of pain conduction, Tuina can not only activate the descending pain inhibition system, accelerate metabolism, reduce the concentration of inflammatory substances in the joints, but also increase the level of β-endorphins and other substances in the serum by regulating the body's release of endogenous morphine-like substances, and play an analgesic effect, thereby relieving the symptoms of pain locally [43] . Exercise has long been considered an important factor in maintaining healthy bones, muscles, and joints, and traditional (resistance, aerobic and flexible) and non-traditional (tai chi, yoga, and water sports) exercises have been shown to be effective in treating knee and hip osteoarthritis [44] .…”

Reconsidering evidence-based management of endometriosis

“…A growing number of reports document the management of endometriosis with complementary therapies ( Porpora et al, 2013 ; Mira et al, 2018 ; Della Corte et al, 2020 ), acupuncture, food intake ( Nirgianakis et al, 2021 ) and exercise ( Langweiler, 2020 ), and more recently traditional Chinese medicine ( Peng et al, 2021 ). These reports are difficult to interpret since the indications and results of these treatments poorly fit EBM standards.…”