Effect of 16,16‐dimethyl prostaglandin E2 on the myoelectric activity of the gastrointestinal tract of the opossum.

Coelho, Júlio Cezar Uili; Gouma, Dirk J.; Li, Y F; Moody, Frank G.; Schlegel, J.U.

doi:10.1113/jphysiol.1986.sp016195

Cited by 5 publications

(1 citation statement)

References 17 publications

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“…The socket was stitched to the skin. The wires were placed in the serosa of the gastrointestinal tract through a 22 gauge needle, the end tied off and the free end was trimmed, as we have described previously [13,14].…”

Section: Methodsmentioning

confidence: 99%

Gastrointestinal motility of patients with Roux‐en‐Y reconstruction

et al. 1992

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The electromyographic activity of the gastrointestinal tract was studied in 28 patients undergoing gastric, biliary, and pancreatic operations with reconstruction of the gastrointestinal tract with a Roux-en-Y limb. The Roux-en-Y limb was constructed 1 to 5 years before the study in 8 patients (chronic Roux-en-Y) and at the operation in which the electrodes were implanted in 20 patients (recent Roux-en-Y). All four phases of the migrating motor complex (MMC) were identified in the gastrointestinal tract, including in the Roux-en-Y limb. The duration of the MMC was 82.4 +/- 22.3 min in the patients with chronic Roux-en-Y and 89.0 +/- 25.1 min in the patients with recent Roux-en-Y. Food ingestion converted the MMC to the fed pattern in the entire gastrointestinal tract, including the Roux-en-Y limb in 16 (76.2%) of 21 recordings of the patients with chronic Roux-en-Y and in 27 (84.4%) of 32 recordings of the patients with recent Roux-en-Y. The duration of the fed pattern was 170 +/- 34 min in the patients with chronic Roux-en-Y and 154 +/- 26 min in the patients with recent Roux-en-Y. The findings of this study indicate that the electromyographic activity of the Roux-en-Y limb is normal during both fasting and fed states, even many years after the construction of the Roux-en-Y.

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Section: Methodsmentioning

confidence: 99%

Gastrointestinal motility of patients with Roux‐en‐Y reconstruction

et al. 1992

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Opioid and nonopioid analgesic drug effects on colon contractions in monkeys

et al. 1995

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Opioid drugs administered postoperatively for pain relief cause increased frequency of nonpropulsive phasic contractions but decreased to absent propulsive migrating contractions in the colon, thus importantly influencing the duration of postoperative ileus. Ketorolac is thought to permit earlier return of bowel function postoperatively compared to morphine. Four monkeys had sets of three strain gauge force transducers implanted on the right and left colon at laparotomy. After recovery, animals were fasted overnight and had colon contractions recorded. After a 1-hr baseline period, 200 micrograms/kg morphine sulfate or 1 mg/kg ketorolac tromethamine was injected intramuscularly and recording continued. Each animal received four injections of each drug. Records were analyzed visually for frequency of phasic on migrating contractions. There was no difference in the frequency of phasic or migrating contractions after injection of ketorolac. Morphine, as expected, increased the frequency of phasic and decreased the frequency of migrating contractions in the colon. Ketorolac does not affect the frequency of colon contractions.

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Motility of Oddi's sphincter: Recent developments and clinical applications

Coelho

Wiederkehr

1996

The American Journal of Surgery

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Effect of 16,16‐dimethyl prostaglandin E2 on the myoelectric activity of the gastrointestinal tract of the opossum.

Cited by 5 publications

References 17 publications

Gastrointestinal motility of patients with Roux‐en‐Y reconstruction

Gastrointestinal motility of patients with Roux‐en‐Y reconstruction

Opioid and nonopioid analgesic drug effects on colon contractions in monkeys

Motility of Oddi's sphincter: Recent developments and clinical applications

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