Effect of 2 referral intervals on diagnostic discordance between cytology and histology at a colposcopy clinic

Abstract

There was no difference in the up- or downgrading of cervical dysplasia between the 2 referral groups.

Is the Correlation between Papanicolaou Smear and Histopathology Results Affected by Time to Colposcopy?

“…CHC of on-site and referral groups in this study were 88.16 and 82.33 percent. Saayman et al 2013 from South Africa reported that there was no difference in the up-or downgrading of cervical dysplasia between early (<6 months) and late (>6 months) colposcopic referral groups (Saayman et al, 2013). This report explained why our TC showed no fluctuation in the correlation between Pap smears and cervical histopathology.…”

The Positive Predictive Value of High-Grade Squamous Intraepithelial Lesion on Cytology for the Histological Diagnosis of Cervical Intraepithelial Neoplasia 2 or Higher: A Systematic Review

“…Regarding the method of cytology, 9 articles used a conventional cytology technique [12, 13, 16, 18, 21-25], 3 used LBC exclusively [15, 26, 27], while 1 used conventional cytology at the beginning of the study (2000–2002) and applied LBC afterwards (2002–2010) [18]. The remaining 15 articles did not clearly describe the method of cytology [5, 9-11, 14, 17, 19, 20, 28-34].…”

Can the careHPV test performed in mobile units replace cytology for screening in rural and remote areas?

“…Treatment is consequently postponed to ameliorate patient anxiety and fear. [45][46][47] Fakokunde et al 48 observed that women who underwent colposcopies after 6 months exhibited less of a tendency to obtain treatment or to develop high-grade lesions compared with a group of women who were examined earlier. The time that elapses between cytological sampling and colposcopy examination varies; however, Pap tests for high-grade lesions are given high priority.…”

“…The ratio between relative light units and a cutoff is calculated by the careHPV system, and samples are considered positive for hr-HPV when this ratio is >1.0. This method can detect 14 types of hr-HPV (types 16,18,31,33,35,39,45, 51, 52, 56, 58, 59, 66, and 68), and >90 specimens can be processed within 2.5 hours. 12,13,19 …”

“…The careHPV test detects 14 types of hr-HPV (types 16,18,31,33,35,39,45,51,52,56,58,59, 66, and 68) in cervical specimens 13,14,19,20 and exhibits high sensitivity and specificity in the detection of precancerous and cancerous cervical lesions. 19,[21][22][23][24] Populations in many Brazilian regions have difficulty accessing public health assistance because many individuals reside in areas that are a distance from medical care facilities, roads (when they exist) are extremely bad, and public transportation is lacking.…”