“…As shown in Table 4 , the majority of the included studies provide evidence that, irrespective of their specific type, tryptamines have the potential to enhance aspects of neuroplasticity (Catlow, Song, Paredes, Kirstein, & Sanchez-Ramos, 2013; Dunlap et al, 2020; Katchborian-Neto et al, 2020; Lima da Cruz et al, 2018; Ly et al, 2018; Marton et al, 2019; Morales-Garcia et al, 2020). Remaining studies, although not directly assessing neurogenesis, reported no adverse effects on behavior or cellular physiology (Castro-Neto et al, 2013; Wankhar, Syiem, Pakyntein, Thabah, & Sunn, 2020; Winne et al, 2020). For instance, Catlow et al (2013) discovered that a single low dose (0.1-0.5 mg/kg) of psilocybin, administered 24 hours prior to a Trace Fear Conditioning test, initially heightened fear response but facilitated fear extinction by the third trial, an effect not observed until the tenth trial in control animals.…”