Effect of 8 Weeks of Incremental Aerobic Training on Inflammatory Mediators, Cardiorespiratory Indices, and Functional Capacity in Obese Children With Bronchial Asthma

Elnaggar, Ragab K; Shendy, Mohammed; Fakharany, Mahmoud S. El

doi:10.1123/pes.2020-0076

Cited by 13 publications

(7 citation statements)

References 33 publications

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“…A total of 12 studies (62%) 10,[27][28][29][30][31][32][33][34][35][36][37] showed that AT induced some change in the immune system inflammatory response, while 9 studies (38%) [38][39][40][41][42][43][44][45] did not show any change in the immune system. In complement, other general benefits were observed such as improvements in the aerobic fitness (10 studies), health-related quality of life (7 studies), clinical control (2 studies), reduction of symptoms of asthma (6 studies), and decrease of airways hyperresponsiveness (2 studies) (Table 1).…”

Section: Resultsmentioning

confidence: 99%

“…Previous studies have shown that AT induces a modulation of the immune system 10,[27][28][29][30][31][32][33][34][35][36][37] . In this sense, the present study speculates on two categories of asthmatics, i) those who practice regular exercise or are trained; ii) and those who are untrained or sedentary.…”

Section: Possible Protective Pathways Against Covid-19 Presented By S...mentioning

confidence: 99%

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People with asthma: care during the COVID-19 pandemic and the importance of regular exercise for the immune system

Silva¹

2022

Motriz: rev. educ. fis.

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To show the possible immunologic pathways of protection for asthmatics against infection of Covid-19 through the capacity of recognition and cytotoxicity to eliminate pathogens improved by regular exercise aerobic. Methods:The bibliographic search was conducted on the following databases: Pubmed/Medline, Scielo, and Scholar Google from 2020 to 2021. The following keywords and Boolean operators were used: asthma, aerobic training (AT), immune system, and Covid-19. Results: After the screening, 349 were initially found, after evaluation only 20 studies had all criteria. Twelve studies showed that AT induces changes in the immune system with a reduction of inflammation. In complement, the literature showed an innate pathway that improves immune function against COVID-19 by reducing angiotensin-converting enzyme 2 (ACE2) in the lung, which seems to hinder the multiplication of the COVID-19 virus in the lung. Apparently, asthmatics patients are less susceptible to respiratory infection caused by COVID-19 because they have low levels of ACE2. Furthermore, trained asthmatics showed a lower risk of infection for SARS-CoV-2. Conclusion:The findings reported that asthmatics people can benefit from AT, and these individuals seem not to be a risk group for covid-19 because they have low levels of ACE2 protein. Taken together, this review reinforces the importance of asthmatic patients be physically active throughout their lifetime, but specially during the pandemic to prevent contamination by SARS-CoV-2.

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Section: Resultsmentioning

confidence: 99%

Section: Possible Protective Pathways Against Covid-19 Presented By S...mentioning

confidence: 99%

People with asthma: care during the COVID-19 pandemic and the importance of regular exercise for the immune system

Silva¹

2022

Motriz: rev. educ. fis.

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“…Table 1 shows the characteristics of the 27 included studies, which included a sample of 1268 randomized subjects (695 were randomized to the exercise group); the mean age was 12.6 years (range 5.1-17.0 years). The authors classified the subjects as obese according to different classifications, such as BMI above the 95th percentile [21][22][23][24][25][26][27] ; BMI above the 97th percentile for age and sex alone [28][29][30][31] or in combination with body fat percentage >25% 28,32 or >34% 33 ; body fat percentage > 30% 34,35 ; BMI adjusted for age and gender 36 ; BMI ≥ 24 37,38 ; BMI ≥ 25 38,39 ; BMI ≥ 30 [40][41][42] ; BMI two standard deviations above the growth reference alone, 43 or in combination with waist circumference >80 cm 44 ; or presence of obesity according to the International Obesity Task Force cut-offs. 45 Nine studies included males only, [24][25][26][27]32,34,38,39,43 seven studies included females only, 23,31,33,35,42,44,…”

Section: Study Characteristicsmentioning

confidence: 99%

“…45 Nine studies included males only, [24][25][26][27]32,34,38,39,43 seven studies included females only, 23,31,33,35,42,44,46 and 11 studies included a mixed sample of males and females. 21,22,[28][29][30]36,37,40,41,45,47 The average study duration was 12 weeks (range 6-26), the frequency was three times per week (range 1-5), and the workout duration was 37 min (range 4-70).…”

Section: Study Characteristicsmentioning

confidence: 99%

Adherence and dropout in exercise‐based interventions in childhood obesity: A systematic review of randomized trials

Guijo,

do Prado,

de Araújo

et al. 2024

Obesity Reviews

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Our objective was to systematically examine the characteristics of exercise interventions on adherence and dropout in children and adolescents with obesity. PubMed, Embase, PsycINFO, Lilacs, Scielo, and The Cochrane Central Register of Controlled Trials and reference lists of relevant articles were searched. We included randomized controlled trials with exercise interventions for pediatric patients with obesity presenting data on dropout and/or adherence. Two reviewers screened the records independently for eligibility with disagreements being resolved by a third reviewer. Twenty‐seven studies with 1268 participants were included. Because of high heterogeneity and poor reporting of adherence, it was not possible to perform a meta‐analysis. Dropout prevalence was calculated, and subgroup analyses comparing different types of exercise and a meta‐regression with potential moderators were performed. We found a dropout rate of 13%. Subgroup analyses did not identify significant differences. The duration of the exercise presented a moderating effect on dropout, suggesting that longer exercise sessions may lead to higher dropout in children and adolescents with obesity. Because of the poor adherence data, it is not clear which exercise characteristics may moderate adherence. To improve the quality of childhood obesity care, it is mandatory that future studies present adherence data. Systematic review registration: PROSPERO CRD42021290700.

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“…In individuals with COPD, HRR improves following exercise training programs or through oxygen supplementation in those with chronic hypoxemia ( Scalvini et al, 1999 ; Gimeno-Santos et al, 2014 ). Obese children with bronchial asthma undergoing pulmonary rehabilitation showed a significant improvement in cardiorespiratory function and HRR, as well as in the inflammatory profile and functional capacity ( Elnaggar et al, 2021 ). However, to the best of our knowledge, no study has evaluated the effects of exercise training on HRR in adult individuals with asthma.…”

Section: Introductionmentioning

confidence: 99%

Effect of pulmonary rehabilitation on heart rate recovery in adult individuals with asthma or chronic obstructive pulmonary disease

Zampogna

Ambrosino²,

Oliva³

et al. 2022

Front. Pharmacol.

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Introduction: Heart rate recovery (HRR) after exercise is a marker of disease severity and prognosis in cardiovascular and respiratory disorders. More than 30% of adult individuals with asthma may show a slow HRR. Pulmonary rehabilitation improves exercise capacity in individuals with asthma or chronic obstructive pulmonary disease (COPD).Aim: The study aimed to evaluate the effect of pulmonary rehabilitation on HRR in individuals with asthma as compared to those with COPD.Methods: Retrospective analysis of HRR one minute after the six-minute walking test (6MWT) was performed before and after an exercise training program. The COPD Assessment Test (CAT), Barthel Index-Dyspnea (BI-D), Medical Research Council (MRC) score for dyspnea, and the Five-Times-Sit-to-Stand test (5STS) were also assessed as secondary outcome measures.Results: Slow HRR prevalence was significantly lower in individuals with asthma than with COPD (29.1 vs. 46.7%, respectively: p = 0.003). Post-program HRR did not change in more than 70% of individuals in either population and improved in 16% of both populations, whereas it actually worsened in 12 and 10% of individuals with asthma and COPD, respectively. The outcome measures significantly improved in both populations, irrespective of baseline HRR.Conclusion: In individuals with asthma or COPD, exercise training does not significantly improve HRR.

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Effect of 8 Weeks of Incremental Aerobic Training on Inflammatory Mediators, Cardiorespiratory Indices, and Functional Capacity in Obese Children With Bronchial Asthma

Cited by 13 publications

References 33 publications

People with asthma: care during the COVID-19 pandemic and the importance of regular exercise for the immune system

People with asthma: care during the COVID-19 pandemic and the importance of regular exercise for the immune system

Adherence and dropout in exercise‐based interventions in childhood obesity: A systematic review of randomized trials

Effect of pulmonary rehabilitation on heart rate recovery in adult individuals with asthma or chronic obstructive pulmonary disease

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