Effect of a delay in definitive surgery in melanoma on overall survival: A NCDB analysis.

Basnet, Alina; Wang, Dongliang; Sinha, Shreya; Sivapiragasam, Abirami

doi:10.1200/jco.2018.36.15_suppl.e21586

Cited by 13 publications

(19 citation statements)

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“… In cutaneous melanoma, Conic et al demonstrated a higher risk of death when the treatment was received between 90 and 119 days after biopsy compared to when it was done within 30 days of biopsy (HR = 1.09 [1.01-1.18]; (p = 0.03)) ( Conic et al, 2018 ). Likewise, five-year overall survival was notably lower in patients who underwent surgery after more than 60 days following diagnosis, compared to patients with time to surgery less than 30 days (72.7% vs 80%) ( Basnet et al, 2018 ). As regards cervical cancer, patients who received treatment between 90 and 180 days after diagnosis had a 1.33 times higher risk of death than those who received treatment within 90 days ( Chen et al, 2019 ).…”

Section: Resultsmentioning

confidence: 99%

Cancer management during the COVID-19 pandemic: Choosing between the devil and the deep blue sea

Boutros

Moujaess

Kourié

2021

Critical Reviews in Oncology/Hematology

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Section: Resultsmentioning

confidence: 99%

Cancer management during the COVID-19 pandemic: Choosing between the devil and the deep blue sea

Boutros

Moujaess

Kourié

2021

Critical Reviews in Oncology/Hematology

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“…In a study of 986 patients with melanoma who were managed with wide local excision, the timing from biopsy to wide local excision did not remarkably affect overall survival on multivariable analysis 4 . On the other hand, a retrospective study using the National Cancer Data Base reported notably worse survival for patients with stages I to III melanoma who experienced a delay of more than 2 months from diagnosis to final surgical management compared with patients treated within 2 months of diagnosis 5 . Another study of National Cancer Data Base similarly reported that delays of more than 30 days from biopsy to final surgery were associated with worse survival for patients with early melanoma 6 .…”

Section: Methodsmentioning

confidence: 99%

“…4 On the other hand, a retrospective study using the National Cancer Data Base reported notably worse survival for patients with stages I to III melanoma who experienced a delay of more than 2 months from diagnosis to final surgical management compared with patients treated within 2 months of diagnosis. 5 Another study of National Cancer Data Base similarly reported that delays of more than 30 days from biopsy to final surgery were associated with worse survival for patients with early melanoma. 6 Tejero-Vasaquez and Nagore developed a rate of growth model to estimate the effect of COVID-19 lockdown on melanoma thickness and prognosis.…”

Section: Melanoma Diagnosis and Surgery In The Era Of Covid-19mentioning

confidence: 99%

Melanoma and COVID ‐19: A narrative review focused on treatment

Elmas

Demirbaş

Düzayak

et al. 2020

Dermatologic Therapy

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Melanoma is the most severe form of skin cancer and its incidence has increased over the past few decades. COVID-19 pandemic affected the diagnosis and management of many diseases including melanoma. In this study, we aimed to provide a review focused on the diagnosis and management of melanoma in the era of COVID-19. A comprehensive search was conducted on PubMed, Web of Science, and Google Scholar databases using the keywords "melanoma," "coronavirus," "COVID 19," and "SARS-CoV-2." The relevant guidelines published by the European Society for Medical Oncology and the National Comprehensive Cancer Network were also included. The current guidelines recommend that surgical interventions for new diagnosis of invasive primary melanoma, patients with postoperative complications, wide resection and sentinel lymph node biopsy for newly diagnosed T3-T4 melanoma, and planned surgical procedures for patients in neo-adjuvant trials should be prioritized. Surgical treatment of T3/T4 melanomas should be prioritized over T1/T2 melanomas except for any melanoma in which large clinical residual lesion is visible. Adjuvant therapies can be postponed for up to 12 weeks depending on the local center circumstances. PD-1 inhibitor monotherapy is recommended for patients starting immunologic therapy. Combination immunotherapy is still considered suitable for patients with higher-risk disease. Encorafenib and binimetinib should be prioritized for patients requiring BRAF-targeted therapy due to the lower chance of symptoms mimicking COVID-19 infection.

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“…Although the study by Richard et al [ 34 ], recorded an average delay of 2 months, the author states that this period is awfully long for this population, as at this time several campaigns were carried out in France. Several studies reported that the patient’s delay was demonstrated in Table 2 [ 30 - 32 , 35 - 40 ].…”

Section: Early Diagnosis and Its Current Trendsmentioning

confidence: 99%

Cutaneous Malignant Melanoma: A Review of Early Diagnosis and Management

Naik¹

2021

World J Oncol

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Cutaneous melanoma (CM) is a malignant tumor formed from pigment-producing cells called melanocytes. It is one of the most aggressive and fatal forms of skin malignancy. In the last decades, CM’s incidence has gradually risen, with 351,880 new cases in 2015. Since the 1960s, its incidence has increased steadily, in 2019, with approximately 96,000 new cases. A greater understanding of early diagnosis and management of CM is urgently needed because of the high mortality rates due to metastatic melanoma. Timely detection of melanoma is crucial for successful treatment, but diagnosis with histopathology may also pose a significant challenge to this objective. Early diagnosis and management are essential and contribute to better survival rates of the patient. To better control this malignancy, such information is expected to be particularly useful in the early detection of possible metastatic lesions and the development of new therapeutic approaches. This article reviews the available information on the early diagnosis and management of CM and discusses such information’s potential in facilitating the future prospective.

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Effect of a delay in definitive surgery in melanoma on overall survival: A NCDB analysis.

Cited by 13 publications

References 0 publications

Cancer management during the COVID-19 pandemic: Choosing between the devil and the deep blue sea

Cancer management during the COVID-19 pandemic: Choosing between the devil and the deep blue sea

Melanoma and COVID ‐19: A narrative review focused on treatment

Cutaneous Malignant Melanoma: A Review of Early Diagnosis and Management

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