Effect of a desensitizing dentifrice on dentinal hypersensitivity

Ong, G. B.; Strahan, J. D.

doi:10.1111/j.1600-9657.1989.tb00364.x

Cited by 16 publications

(10 citation statements)

References 17 publications

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“…One disadvantage is that OTC desensitizing products may take up to 2-4 weeks to relieve symptoms whereas in theory a practitioner-applied therapy ideally may provide immediate relief of discomfort. although in some situations, pulpal extirpation or extraction of the offending tooth may be the treatment of choice (115). within 2 weeks) would, however, appear to be a significant advancement in the treatment of DH/RDS.…”

Section: Management Of Dh/rdsmentioning

confidence: 99%

Advances in the treatment of root dentine sensitivity: mechanisms and treatment principles

Gillam¹,

Orchardson²

2006

Endodontic Topics

108

116

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There are limited studies specifically on the prevalence of root dentine hypersensitivity or root sensitivity per se; most of the published information relates to the prevalence of dentine hypersensitivity (DH). Several investigators have suggested that there may be some justification on the basis of differing pathologies of distinguishing between those individuals complaining of DH who have relatively healthy mouths with those who complain of DH as a result of periodontal disease and/or its treatment. It is generally recognized that those individuals diagnosed with periodontal disease and having periodontal therapy including scaling procedures may have a higher prevalence than those who present with healthy mouths and evidence of gingival recession. The availability of a vast array of treatments, however, would indicate either that there is no one effective desensitizing agent for completely resolving the discomfort or that the condition, due to its highly subjective nature, is difficult to treat irrespective of the available treatment options. The importance of implementing preventative strategies in identifying and eliminating predisposing factors in particularly erosive factors (e.g. dietary acids) cannot be ignored if the practitioner is going to treat this troublesome clinical condition successfully. This paper will review the published literature and provide information as to the prevalence of the condition, its etiology and causal factors, as well as recommendations for the clinical management of the problem.

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Section: Management Of Dh/rdsmentioning

confidence: 99%

Advances in the treatment of root dentine sensitivity: mechanisms and treatment principles

Gillam¹,

Orchardson²

2006

Endodontic Topics

108

116

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“…The exploratory SnF 2 toothpaste used in this study has been shown in clinical trials to reduce the severity of DH pain compared with conventional fluoride toothpaste in studies ranging from single brushing to 14 days' twice-daily brushing [22][23][24]. Similar formulations have shown benefits after 4 and 8 weeks of use [28,29].…”

Section: Discussionmentioning

confidence: 99%

“…The results from this study strengthen this theory, because viewing the dentine surface from above did not show any significant difference in the degree of occlusion from the SnF 2 containing toothpaste after 8 days of treatment. Clinical studies using the same toothpaste have shown it to provide relief from DH [22][23][24]. The model may therefore need to be further modified to include cross-sectional imaging of the tubules to identify occluding particles further down inside them.…”

Section: Discussionmentioning

confidence: 99%

“…The ability of this new formulation to relieve DH is being assessed in a comprehensive programme of clinical trials [22][23][24]. An in situ model has been developed for clinical evaluation of tubule occlusion properties of toothpastes [25] using a conventional scanning electron microscope (SEM) and applying a replica technique to identify differences between positive and negative control DH toothpastes.…”

Section: Introductionmentioning

confidence: 99%

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Assessment of tubule occlusion properties of an experimental stannous fluoride toothpaste: A randomised clinical in situ study

West

Seong

Hellin

et al. 2018

Journal of Dentistry

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Keywords:Crossover Dentine hypersensitivity Dentinal tubule occlusion in situ model Stannous fluoride Toothpaste A B S T R A C TObjectives: To evaluate the ability of a modified in situ model to differentiate dentinal tubule occlusion properties of toothpaste formulations over 10 days of treatment.Methods: This was a single-centre, three-treatment period, crossover, randomised, single-blind study with healthy participants wearing two lower oral appliances, each retaining four dentine samples, for 10 treatment days during each period of the study. Samples were power-brushed ex vivo twice on each treatment day with a Test toothpaste containing 0.454% stannous fluoride, a Control fluoride toothpaste containing 0.76% sodium monofluorophosphate, or mineral water. Dentine samples were subjected to in situ acid challenge (orange juice) on Days 9 and 10. Scanning electron microscopy images obtained at baseline and after 1, 4, 8 and 10 days of treatment were graded for degree of surface coverage by four calibrated examiners; the primary study endpoint was Day 8. Results: After 4, but not 8, days' treatment, the degree of tubule occlusion increased in the dentine samples treated with the Test or Control toothpastes compared with the water-treated samples (p < 0.01 and p < 0.05, respectively). Following the acid challenge (Day 10), there was a statistically significantly greater degree of occlusion in the Test toothpaste-treated dentine samples compared with those treated with water (p < 0.01). No other comparisons were statistically significant. All study treatments were generally well-tolerated. Conclusions: This modified in situ model was unable to demonstrate statistically significant between-treatment differences in dentinal tubule occlusion after 8 days. Conversely, there are recognised developments that could be made to better identify product differences. Clinicaltrials.gov: NCT02768194. Clinical significance: Dentine hypersensitivity can be managed through brushing with stannous fluoride toothpastes, which occlude patent dentine tubules. Clinical studies measure pain but in situ models are needed to demonstrate occlusion intra-orally. However, this study did not demonstrate superior occlusion with stannous toothpaste; further methodological development is required to investigate its mode of action.

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“…As indicated in Chap. Other miscellaneous treatment approaches have also been recommended, for example, occlusal adjustment associated with cervical abfraction lesion (Coleman et al 2003 ), crown restorations, root coverage surgery, pulp extirpation, extraction (Ong and Strahan 1989 ), homoeopathic remedies (Plantago) ( www.hpathy.com ), propolis (Mahmound et al 1999 ) and hypnosis Eitner et al 2010 ). Examples of these products are resins, varnishes, primers, dentine bonding agents and glass ionomer cements which contain fl uoride, aluminium, potassium or ferric oxalates; silica or calcium-containing materials; and protein precipitants to decrease dentin permeability or block the fl uid movement through dentin (Tables 5.3 and 5.4 ).…”

Section: Restorative Approachesmentioning

confidence: 99%

Clinician's Guide to the Diagnosis and Management of Tooth Sensitivity

Taha¹,

Clarkson²

2014

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Effect of a desensitizing dentifrice on dentinal hypersensitivity

Cited by 16 publications

References 17 publications

Advances in the treatment of root dentine sensitivity: mechanisms and treatment principles

Advances in the treatment of root dentine sensitivity: mechanisms and treatment principles

Assessment of tubule occlusion properties of an experimental stannous fluoride toothpaste: A randomised clinical in situ study

Clinician's Guide to the Diagnosis and Management of Tooth Sensitivity

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