Effect of a gluten-free diet on gastrointestinal symptoms in celiac disease

Murray, Joseph A.; Watson, Tureka; Clearman, B; Mitros, Frank A.

doi:10.1093/ajcn/79.4.669

Cited by 259 publications

(178 citation statements)

References 17 publications

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“…However, the early recognition and treatment of CD are recommended, as glu- Dickey et al 30 57 EmA 6 (11%) 4 (7%) Kingham et al 31 67 -4 (6%) 4 (6%) Gillett et al 32 378 tTGA, EmA 11 (2.6%) 5 (1.3%) Floreani et al 33 87 EmA 3 (3.4%) 3 (3.4%) Volta et al 34 173 tTGA, EmA 7 (4%) 7 (4%) Chatzicostas et al 35 62 tTGA, EmA 6 (10%) 0* Bardella et al 36 65 AGA, EmA 0 -Niveloni et al 37 10 AGA, EmA ten restriction improves the symptoms attributable to CD and can also reduce the risk of complications (malabsorption, osteoporosis, and malignant neoplasms). 44,45 Autoimmune Hepatitis (AIH) Prevalence. Two studies found that the prevalence of CD in patients with AIH was 4% to 6.4%.…”

Section: Primary Biliary Cirrhosismentioning

confidence: 99%

“…Again, treatment with a GFD is necessary to improve symptoms of CD (if present) and to avoid severe chronic complications of CD. 44,45 Primary Sclerosing Cholangitis…”

Section: Primary Biliary Cirrhosismentioning

confidence: 99%

“…The body mass index was Ͼ25 kg/m 2 (overweight or obese) in 27% of American patients at the time of CD diagnosis. 44 A study of 54 patients with diet-resistant nonalcoholic fatty liver disease (64% with steatohepatitis) found a prevalence of 10% and 4.3% for tTGA and EmA, respectively. The diagnosis of CD was confirmed by intestinal biopsy in 3.4% of the patients.…”

Section: Nonalcoholic Fatty Liver Diseasementioning

confidence: 99%

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The liver in celiac disease

2007

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Celiac disease is a common (1% prevalence) chronic immune-mediated disorder of the small intestine induced by dietary wheat, barley, and rye. Several hepatic disorders have been described in association with celiac disease. Isolated hypertransaminasemia with nonspecific histologic changes in a liver biopsy is the commonest hepatic presentation of celiac disease. A gluten-free diet normalizes liver enzymes and histologic changes in most patients. Moreover, celiac disease can coexist with autoimmune liver disorders such as autoimmune hepatitis, primary biliary cirrhosis, and primary sclerosing cholangitis. Celiac disease has increasingly been reported with a variety of other liver diseases. Thus, the hepatologist needs to consider celiac disease in the differential of abnormal liver blood tests and to be aware of the clinical implications of this frequent disease in patients with liver disorders. The possible mechanisms of liver injury and those common factors that explain the association of celiac disease with liver disorders are discussed. The aims of this article are (1) to review the spectrum and pathogenesis of liver injury related to celiac disease and (2) to provide direction to those caring for patients with chronic liver diseases regarding the detection and effective treatment of celiac disease. (HEPATOLOGY 2007;46:1650-1658

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Section: Primary Biliary Cirrhosismentioning

confidence: 99%

“…Again, treatment with a GFD is necessary to improve symptoms of CD (if present) and to avoid severe chronic complications of CD. 44,45 Primary Sclerosing Cholangitis…”

Section: Primary Biliary Cirrhosismentioning

confidence: 99%

Section: Nonalcoholic Fatty Liver Diseasementioning

confidence: 99%

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The liver in celiac disease

2007

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“…Other several studies were established subsequently about this relationship (7). The effect of GFD on natural history of AIH is not clear but GFD is necessary to improve the symptoms of CD (25).…”

Section: Discussionmentioning

confidence: 99%

Fluctuation of liver transaminases with gluten-free diet compliance of a patient with celiac disease and autoimmune hepatitis; a case report

Uyar¹,

Harmandar²,

Gulenay³

et al. 2017

J Turgut Ozal Med Cent

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Although the association of celiac disease with autoimmune hepatitis is well-known, the effect of gluten-free diet on autoimmune hepatitis progression is poorly deafined. We described a patient with celiac disease coexisting with autoimmune hepatitis and effectiveness of gluten-free diet on both diseases. A young patient with eleveted serum liver transaminases was diagnosed as celiac disease and autoimmune hepatitis according to clinical, laboratory and pathological findings. Clinical complaints and laboratory findings of patients resolved exactly after glutenfree diet. However, liver transaminases eleveted and clinical manifestations re-emerged when he left the diet. Clinicians should consider that other autoimmune diseases may occur in the course celiac disease and gluten-free diet may improve also extra-intestinal manifestations of celiac disease.

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“…Especially, with rising number of patients with gluten sensitivity and celiac disease [2]. In addition to, the rapid change in consumer lifestyle, where gluten-free diet is also associated with weight management and overall health [3,4].…”

Section: Introductionmentioning

confidence: 99%

Production of Gluten-Free Rolled Paper from Broken Rice by Using Different Hydrothermal Treatments

Abdel-Haleem¹

2016

IJNFS

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Abstract:The aim of this study is to produce Gluten-Free rolled paper from broken rice by using different hydrothermal treatments. Pressure parboiling, dry roast parboiling, and popping treatments were applied to enhance the functionality of lowamylose broken rice flour. The effects of hydrothermal treatments on the morphological, physicochemical, as well as sensory properties of the produced Gluten-Free rolled papers were studied. Morphological examination of hydrothermal treated flours showed gelatinized and enlarged starch granules with different shapes, and fractures in the surface, especially in dry roasted parboiled flour. For chemical composition (g/100g), protein (6.7 -3.57), total starch (81.67-76.36) and amylose (17.27 -14.18) significantly decreased in rice papers produced from hydrothermal treated flours, while fat (1.67 -1.82) and ash (1.62 -2.68) significantly increased. In vitro starch digestibility showed a significant increase (80 -99.73 g glucose/ 100g) in rice papers produced from dry roast parboiling and popping treatments. Rice paper batters produced from hydrothermal treatments had a noticeable viscosity pattern characterized by a non-Newtonian pseudoplastic flow behavior. A significant reduction in lightness value (89.77 to 60.42) occurred, while a significant increase in redness (0.33 to 1.54) and yellowness (3.75 -20.59) values were observed in all rice papers produced from hydrothermal-treated flours. Tensile strength (0.14 -0.36 N/mm 2 ) and % elongation at break (43 -57%) significantly increased in rice papers produced from parboiling treatments, while fracture toughness increased (2.76-5.51 N/mm 3/2 ) in rice paper produced from popping treatment. Sensory evaluation indicated significant improvement in freshness, rollability, and the overall scores in rice papers produced from parboiling treatments. Results could be a value addition for processing of low-amylose broken rice flour and delivering high quality rice paper to consumers who are more concerned about Gluten-Free products.

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Effect of a gluten-free diet on gastrointestinal symptoms in celiac disease

Cited by 259 publications

References 17 publications

The liver in celiac disease

The liver in celiac disease

Fluctuation of liver transaminases with gluten-free diet compliance of a patient with celiac disease and autoimmune hepatitis; a case report

Production of Gluten-Free Rolled Paper from Broken Rice by Using Different Hydrothermal Treatments

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