Effect of a Nasal Pillow on Compliance, Nasal Symptoms and Quality of Life in Patients with Obstructive Sleep Apnea Syndrome Using Continuous Positive Airway Pressure Therapy.

Ryan, Suzanne; Jf, Garvey; Swan, Valerie; Behan, Renata; McNicholas, WT

doi:10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1260

Cited by 12 publications

(20 citation statements)

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“…16 We also demonstrated, along with the improvement in adherence, an improvement in quality of life. In contrast, previous studies [7][8][9] did not achieve the same result. Ryan et al 7 conducted a study comparing the 4-week use of dry CPAP, CPAP with heated humidification, and CPAP with additional topical nasal steroid application in 125 subjects with the established diagnosis of OSA (AHI Ն10 events/h).…”

Section: Discussioncontrasting

confidence: 92%

“…AHI ϭ apnea-hypopnea index RDI ϭ respiratory disturbance index NREM1 ϭ non-rapid eye movement 1 NREM2 ϭ non-rapid eye movement 2 NREM3 ϭ non-rapid eye movement 3 REM ϭ rapid eye movement unchanged. 7 Another study by Ruhle et al, 8 which was a 4-week crossover study comparing the use of conventional CPAP with CPAP with heated humidification on 44 subjects with OSA, also only demonstrated the positive effect on dryness of the mouth. However, adherence and quality of life were not altered.…”

Section: Discussionmentioning

confidence: 99%

“…6 More recent studies did not show the positive effects of heated humidification on adherence when heated humidification was used routinely; however, nasal symptoms were significantly improved. [7][8][9] The discrepancy of the results warrants further studies.…”

Section: Introductionmentioning

confidence: 86%

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Effect of Heated Humidification on CPAP Therapy Adherence in Subjects With Obstructive Sleep Apnea With Nasopharyngeal Symptoms

et al. 2016

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BACKGROUND: The addition of heated humidification to CPAP has been shown to improve nasal adverse effects in subjects with obstructive sleep apnea (OSA). However, current data regarding improvement in CPAP adherence is conflicting. Furthermore, there are no data from a tropical climate area with a high humidity level. METHODS: In this prospective randomized crossover study conducted in Thailand, subjects with moderate to severe OSA with nasopharyngeal symptoms post-split-night study were enrolled in the study. Subjects were randomly assigned to receive CPAP with or without heated humidification for 4 weeks and then crossed over. Information on CPAP adherence, quality of life assessed by the Functional Outcomes of Sleep Questionnaire, nasopharyngeal symptoms assessed by a modified XERO questionnaire, and bedroom ambient humidity and temperature data were obtained. RESULTS: Data were collected on 20 subjects with OSA during the period of January to December 2014. Although the addition of heated humidification appeared to improve average hours of use for all days when compared with conventional CPAP, the difference was not statistically significant (CPAP with heated humidification ‫؍‬ 4.6 ؎ 1.7 h/night; conventional CPAP ‫؍‬ 4.0 ؎ 1.7 h/night, P ‫؍‬ .1). However, the addition of heated humidification improved CPAP adherence on the days of use (5.5 ؎ 1.5 h/night) compared with conventional CPAP (5.2 ؎ 1.4 h/night), P ‫؍‬ .033. Quality of life was also improved according to the Functional Outcomes of Sleep Questionnaire score (median 17.6 [interquartile range 3.5]) in the heated humidification group compared with conventional CPAP group (median 17.6 [interquartile range 4.5]), P ‫؍‬ .046. Significant reduction in the dry throat/sore throat symptom was noted only when CPAP with heated humidification was used. CONCLUSIONS: Even in a tropical climate area, CPAP adherence and quality of life appeared to improve when heated humidification was employed in subjects with moderate to severe OSA with nasopharyngeal symptoms post-split-night polysomnography. The improvement may be related to a reduction in the dry throat/sore throat symptom.

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Section: Discussioncontrasting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

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Effect of Heated Humidification on CPAP Therapy Adherence in Subjects With Obstructive Sleep Apnea With Nasopharyngeal Symptoms

et al. 2016

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“…Lastly, the sample size of the current study could be considered limited, especially in comparison with recently published data [29]. Yet, in accordance with the results of the present study, RYAN et al [29] demonstrated that the addition of heated humidification is associated with a decrease in the frequency of nasal symptoms in OSA patients. However, this decrease does not lead to improved adherence to CPAP [30].…”

Section: Sleep-related Disorders I Koutsourelakis Et Alsupporting

confidence: 79%

“…The SNOT-20 is one of the most widely used quality-of-life instruments for a validated evaluation of sino-nasal conditions and is intended for populations with rhinosinusitis [17]. Lastly, the sample size of the current study could be considered limited, especially in comparison with recently published data [29]. Yet, in accordance with the results of the present study, RYAN et al [29] demonstrated that the addition of heated humidification is associated with a decrease in the frequency of nasal symptoms in OSA patients.…”

Section: Sleep-related Disorders I Koutsourelakis Et Almentioning

confidence: 99%

Nasal inflammation in sleep apnoea patients using CPAP and effect of heated humidification

Koutsourelakis¹,

Vagiakis²,

Perraki³

et al. 2010

Eur Respir J

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Nasal continuous positive airway pressure (CPAP) can cause undesirable nasal symptoms, such as congestion to obstructive sleep apnoea (OSA) patients, whose symptoms can be attenuated by the addition of heated humidification. However, neither the nature of nasal symptoms nor the effect of heated humidification on nasal pathophysiology and pathology are convincingly known.20 patients with OSA on nasal CPAP who exhibited symptomatic nasal obstruction were randomised to receive either 3 weeks of CPAP treatment with heated humidification or 3 weeks of CPAP treatment with sham-heated humidification, followed by 3 weeks of the opposite treatment, respectively. Nasal symptom score, nasal resistance, nasal lavage interleukin-6, interleukin-12 and tumour necrosis factor-a and nasal mucosa histopathology were assessed at baseline and after each treatment arm.Heated humidification in comparison with sham-heated humidification was associated with decrease in nasal symptomatology, resistance and lavage cytokines, and attenuation of inflammatory cell infiltration and fibrosis of the nasal mucosa.In conclusion, nasal obstruction of OSA patients on CPAP treatment is inflammatory in origin and the addition of heated humidification decreases nasal resistance and mucosal inflammation.

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Redefining the timing of surgery for obstructive sleep apnea in anatomically favorable patients

2014

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Effect of a Nasal Pillow on Compliance, Nasal Symptoms and Quality of Life in Patients with Obstructive Sleep Apnea Syndrome Using Continuous Positive Airway Pressure Therapy.

Cited by 12 publications

References 0 publications

Effect of Heated Humidification on CPAP Therapy Adherence in Subjects With Obstructive Sleep Apnea With Nasopharyngeal Symptoms

Effect of Heated Humidification on CPAP Therapy Adherence in Subjects With Obstructive Sleep Apnea With Nasopharyngeal Symptoms

Nasal inflammation in sleep apnoea patients using CPAP and effect of heated humidification

Redefining the timing of surgery for obstructive sleep apnea in anatomically favorable patients

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