Effect of a novel fluorapatite-forming calcium phosphate cement with calcium silicate on osteoblasts in comparison with mineral trioxide aggregate

Suzuki, Yusuke; Hayashi, Makoto; Tanabe, Natsuko; Yasukawa, Takuya; Hirano, Yusuke; Takagi, Shōzō; Chow, Laurence C.; Suzuki, Naoto; Ogiso, Bunnai

doi:10.2334/josnusd.57.25

Cited by 8 publications

(11 citation statements)

References 25 publications

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“…Entre os biocerâmicos Bio-C Sealer ® , EndoSequence BC Sealer ® , ProRoot ES ® e o cimento à base de resina epóxi AH Plus ® , observa-se que os biocerâmicos são significativamente biocompatíveis e promovem diferenciação osteoblástica (De-Deus et al, 2012;Suzuki et al, 2015;Troiano et al, 2018;Giacomino et al, 2019;López-García et al, 2019). Entretanto, o MTA Fillapex ® apresenta efeito citotóxico grave quando exposto de maneira in vitro, nas células-tronco germinais dentárias humanas e esse efeito não diminui com o tempo (Güven et al, 2013).…”

Section: Discussionunclassified

Cimentos biocerâmicos em endodontia: revisão integrativa

Silva

Wanderley

et al. 2020

RSD

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Introdução: Os cimentos endodônticos desempenham papel importante no êxito terapêutico. As propriedades dos biocerâmicos representam grandes avanços, visando suprir as necessidades dos demais materiais disponíveis no mercado. Objetivo: Realizar uma revisão de literatura sobre as propriedades e características dos cimentos biocerâmicos. Metodologia: Foi realizada uma revisão de literatura integrativa, através de busca na base de dados Medline (Medical Literature Analysis and Retrievel System Online). Os descritores utilizados para busca foram "bioceramic", "endodontic sealer” e "endodontic treatment". Os critérios de inclusão foram artigos publicados nos últimos dez anos, de 2010 a 2020, estudos laboratoriais e clínicos, no idioma inglês e publicados na íntegra. Foram excluídos artigos duplicados, revisões de literatura, estudos com apenas o resumo disponível, dissertações, monografias e teses. Resultados: Após a busca dos artigos, 50 artigos sobre cimentos biocerâmicos foram incluídos na revisão de literatura. Os artigos tinham como objetivos de estudo as propriedades químicas, físicas e biológicas, além da adaptação marginal, vedamento apical e o comportamento dos materiais frente ao retratamento. Conclusão: Pode-se concluir que a utilização dos cimentos biocerâmicos apresenta aspectos favoráveis e promissores, embora mais estudos clínicos precisem ser realizados.

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Section: Discussionunclassified

Cimentos biocerâmicos em endodontia: revisão integrativa

Silva

Wanderley

et al. 2020

RSD

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“…However, the term 'biocompatibility' in general refers to the degree of a material's toxicity, which is usually measured by means of phenotyping, monitoring the inflammatory response or the metabolic activity of target cells, whilst behavioural parameters such as cell division or differentiation are not addressed. Actually, a number of reports show that cellular proliferation and differentiation are diminished by MTA if compared to native controls (Nakayama et al 2005, Hakki et al 2009, Willershausen et al 2013, Suzuki et al 2015, and it is not surprising that cells in contact with any repair material perform worse compared to untouched controls. A subtle but important difference is that MTA indeed supports the cellular performance if compared to other endodontic materials (Nakayama et al 2005), which were not investigated in the framework of this study.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the bioactivity of fluoride‐enriched mineral trioxide aggregate on osteoblasts

et al. 2018

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“…FHA has a better osteointegration in bone tissue in comparison to HA in vivo [82]. It has good biocompatibility, low solubility, and good thermal and chemical stability [83]. Therefore, FHA is a good therapeutic candidate in the treatment of osteoporosis.…”

Section: Fluoride Substituted Ha (Fha)mentioning

confidence: 99%

“…Fluoride ions (F -) released from FHA was found to promote the in vitro osteoblastic activities by enhancing the cell adhesion, proliferation, differentiation and mineralization (Table 2) [83].…”

Section: Fluoride Substituted Ha (Fha)mentioning

confidence: 99%

Substituted hydroxyapatite: a recent development

Jiang

Yuan

Huang

2019

Materials Technology

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Hydroxyapatite (HA, Ca10(PO4)6(OH)2) constitutes the major inorganic hard tissues, such as bone and teeth. Various substitutions in the apatite structure have been developed for a wide range of biomedical applications, such as the bone repair and tissue regenerations; bioactive and/or antibacterial coating for medical devices, biomarkers or carriers in drug/gene delivery systems, and the biomagnetic agents for cancer treatment. In this review, the recent development on substituted HA was overviewed from the aspects of enhanced osteoconductivity and multifunctionality of mono-and multi-cationic and anionic substitutions.

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Effect of a novel fluorapatite-forming calcium phosphate cement with calcium silicate on osteoblasts in comparison with mineral trioxide aggregate

Cited by 8 publications

References 25 publications

Cimentos biocerâmicos em endodontia: revisão integrativa

Cimentos biocerâmicos em endodontia: revisão integrativa

Evaluation of the bioactivity of fluoride‐enriched mineral trioxide aggregate on osteoblasts

Substituted hydroxyapatite: a recent development

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