Effect of a novel prime‐and‐rinse approach on short‐ and long‐term dentin bond strength of self‐etch adhesives

Abstract

Effect of a novel prime-and-rinse approach on short-and long-term dentin bond strength of self-etch adhesives. Eur J Oral Sci 2019; 127: 547-555. © 2019 Eur J Oral SciThis study investigated the effects of the prime-and-rinse approach, using a 10methacryloyloxydecyl dihydrogen phosphate (MDP)-containing primer, on the short-and long-term dentin microtensile bond strengths (MTBSs) of mild self-etch adhesives. Half of sixty human midcoronal dentin surfaces were polished as control (self-etch approach), and the other half were polished and further treated with a 15% MDP-containing primer and thoroughly sprayed with water as prime-and-rinse approach. The dentin surfaces were treated with a self-etch adhesive, and a composite resin was placed on the surfaces. The following materials were used: Clearfil S3 Bond+Clearfil Majesty; G-Bond+Gradia Direct; Adper Easy One+Z250; and i Bond+Charisma. The MTBS was examined after 24 h and 14 months in water storage. The resin-dentin interfaces were analysed using scanning electron microscopy/ transmission electron microscopy. Pretreated dentin surfaces were further analysed using scanning electron microscopy and micro-Raman spectroscopy. Compared with the self-etch approach, the prime-and-rinse approach significantly increased the dentin MTBS, regardless of the duration of storage. The scanning electron microscopy/ transmission electron microscopy findings revealed that the prime-and-rinse approach removed most of the dentin smear layer. The Raman spectra of the MDP-treated dentin reveal the characteristic spectra of collagen, hydroxyapatite, and the monomer. Therefore, the prime-and-rinse approach using MDP-containing primers prior to the application of mild self-etch adhesives significantly increases the short-and long-term MTBS of dentin.

Glycerol Phosphate Dimethacrylate: An Alternative Functional Phosphate Ester Monomer to 10-Methacryloyloxydecyl Dihydrogen Phosphate for Enamel Bonding

“…Three universal adhesives used here (TNBU, SBU, and CUBQ) contained MDP, one of the most effective functional monomers that can combine with HAp . The present NMR observations detected Ca–O–P bonds in HAp conditioned by TNBU, SBU, and CUBQ, but not in HAp conditioned by OV primer, suggesting MDP-Ca salts formed.…”

“…19,20 Many of today's universal adhesives incorporate the functional phosphate ester monomer 10-methacryloyloxydecyl dihydrogen phosphate (MDP), which is considered one of the most effective monomers for strong binding to HAp. 21 Another functional phosphate ester monomer that has been used in dental adhesives is glycerol phosphate dimethacrylate (GPDM), which has been utilized in E&R adhesives, SE adhesives, and self-adhesive composite cements. It is presumed that the higher etching efficacy of GPDM-based SE adhesives may result in equally effective bonding compared to phosphoric acid etching.…”

Dual Functions of MDP Monomer with De- and Remineralizing Ability

“…Some unpolymerized MDP monomer remained at the dentin surface when dentin surface was treated with MDP-containing conditioner and thoroughly water-sprayed (Li et al 2019). This mineralization induced by the MDP monomer might be limited because there was a limited amount of calcium and phosphate source at the resin–dentin interface.…”

“…This study directly demonstrated that MDP monomer with no polymeric additives could induce the biomimetic mineralization of collagen and demineralized dentin. Some unpolymerized MDP monomer remained at the dentin surface when dentin surface was treated with MDPcontaining conditioner and thoroughly water-sprayed (Li et al 2019). This mineralization induced by the MDP monomer might be limited because there was a limited amount of calcium and phosphate source at the resin-dentin interface.…”