Effect of a resin-modified glass-ionomer with calcium on enamel demineralization inhibition: an in vitro study

Abstract

We assessed the effect of a new coating material based on resin-modified glass-ionomer with calcium (Ca) in inhibiting the demineralization of underlying and adjacent areas surrounding caries-like lesions in enamel. The measures used were surface hardness (SH) and cross-sectional hardness (CSH). Thirty-six bovine enamel specimens (3 × 6 × 2 mm) were randomly allocated into three groups (n = 12): No treatment (NT); resin-modified glass-ionomer with Ca (Clinpro XT Varnish, 3M ESPE) (CL), and fluoride varnish (Duraphat, Colgate) (DU). The specimens were subjected to alternated immersions in demineralizing (6 h) and remineralizing solutions (18 h) for 7 days. SH measurements were conducted at standard distances of 150, 300, and 450 µm from the treatment area. CSH evaluated the mean hardness profile over the depth of the enamel surface and at standard distances from the materials. The energy-dispersive X-ray spectroscopy analysis was conducted to evaluate the demineralization bands created on the sublayer by % of calcium (Ca), phosphorus (P), and fluoride (F). Ca/P weight ratio was also calculated. Based on SH and CSH measurements, there was no difference between groups at the distances 150 µm (p = 0.882), 300 µm (p = 0.995), and 450 µm (p = 0.998). Up to 50 µm depth (at 150 µm from the treatment area), CL showed better performance than DU ( p< 0.05). NT presented higher loss of Ca and P than CL and DU (p < 0.05). There was no significant difference in the % of F ion among the three groups. The new coating material was similar to F varnish in attenuating enamel demineralization.

Comparative Study on the Effect of Diode Laser Application on the Longevity of Fluoride Release from Three Different Fluoride Varnishes: An in vitro Study

“…Based on resin modified glass ionomer technology, fluoride release would be slower and extended (22) . The results from this study, regarding fluoride release of Clinpro XT, are consistent with the conclusion of Virupaxi, et al (8) , who stated that Clinpro XT had the highest fluoride mean release when compared to conventional fluoride varnishes, after evaluating the longevity of fluoride release from Clinpro XT, Flouritop SR and Flourprotector over a period of 6 months through salivary fluoride estimation, after 1 week, 1 month, 3 months and 6 months from varnishes application.The current study's findings, on the other hand, differ from those of Scotti et al (23) , who investigated the effect of Clinpro XT and Duraphat varnishes on inhibiting demineralization of underlying and adjacent areas surrounding carieslike lesions in enamel and measuring fluoride release. By the end of their study, they concluded that there was no statistically significant difference in the percentage of fluoride release among the three groups; this difference in conclusion could be attributed to the fact that they measured fluoride release in demineralized tooth structure, rather than sound tooth structure, as in the current study.…”

Evaluation of the state and shade of white spot lesions after treatment with different remineralizing agents ( An in-vivo comparative study ).

“…These results also are in agreement with Scotti et al (16) , they assessed that Clinpro XT showed better performance than fluoride. This fact could have occurred due to the chemical bond between glass ionomer of Clinpro XT Varnish and the tooth surface, which allows longer maintenance time.…”

Incorporation of zwitterionic materials into light-curable fluoride varnish for biofilm inhibition and caries prevention

“…It is considered to have advantages of longevity and sustainability, and it also provides good maneuverability with prolonged working times and short setting times achieved by light curing. It has been reported that the effectiveness of LCFV in the inhibition of enamel demineralization is comparable to conventional FV 8 . Moreover, recent clinical studies have shown that LCFV could effectively prevent enamel demineralization for a longer term compared with the conventional FV 9,10 .…”