Effect of a wild blueberry (Vaccinium angustifolium) drink intervention on markers of oxidative stress, inflammation and endothelial function in humans with cardiovascular risk factors

Abstract

In conclusion, the consumption of the WB drink for 6 weeks significantly reduced the levels of oxidized DNA bases and increased the resistance to oxidatively induced DNA damage. Future studies should address in greater detail the role of WB in endothelial function.

Association of flavonoid-rich foods and flavonoids with risk of all-cause mortality

“…These associations remained after adjusting for dietary pattern, suggesting that the 191 oxidative stress and inflammation [29][30][31][32][33] . The strongest beneficial relation with all-cause mortality 195 was observed with the frequency of red wine consumption, which remained even after adjusting 196 for total alcohol consumption, which has been shown to be a strong predictor of all-cause 197 mortality 34 .…”

Different postprandial acute response in healthy subjects to three strawberry jams varying in carbohydrate and antioxidant content: a randomized, crossover trial

“…For these reasons, studies have been designed to assess the health effects of fruits and fruit-derived products such as juices, jams, or syrup in humans [10,11]. Thus, it has been hypothesized that, like fresh fruits, these products could induce healthy properties due to the antioxidant and fiber content, occurring naturally or added [12], as well as being involved in carbohydrate metabolism regulation [13,14].…”

Acute cigarette smoking impairs microvascular function in young moderate smokers: A potential model for studying vasoactive properties of food bioactives

“…The experimental model described here, where a decrease of RHI is easily induced by cigarette smoking, could be useful in studying the impact of dietary vasoactive compounds such as anthocyanins (previously tested in our long term study) [ 14 ] in modulating peripheral arterial function. It has been recently argued that the relationship between food and "pharma" is not well-defined and sometimes it may overlap.…”

“…Based on results obtained in a previous study [ 14 ] where we failed to demonstrate a significant modulation of endothelial function (evaluated through EndoPAT-2000) following regular intake of an anthocyanin-rich product in subjects with different risk factors for cardiovascular disease, we embarked on utilizing smoking as a stressor to develop a model that may better demonstrate the effect of dietary vasoactive compounds. The aim of the present study is to evaluate whether peripheral arterial tone (PAT) technology is able to detect the acute effects of a single cigarette smoking on RHI and dAix in a homogeneous group of young healthy male smokers.…”