2007
DOI: 10.2334/josnusd.49.67
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Effect of a xylitol and fluoride containing toothpaste on the remineralization of human enamel in vitro

Abstract: The aim of this study was to examine the effect of a fluoride and xylitol containing toothpaste on the remineralization of human enamel using Quantitative Light-induced Fluorescence (QLF). Human extracted teeth were cut longitudinally into three or four parts, and artificial subsurface lesion windows (2 mm × 3 mm) were created by immersion in demineralizing solution. Each enamel sample (n = 7) was treated for 3 min at 25°C twice a day for consecutive 14 days with the slurry of a silica-based toothpaste 1) with… Show more

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Cited by 33 publications
(24 citation statements)
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“…Artificial enamel lesions were created on tooth surfaces by immersion in a demineralizing solution (CaCl 2: 12 mM; KH2PO4: 10 mM; lactic acid: 50 mM; NaCl: 100 mM; pH=4.5) at 37°C for 6 h, followed by immersion in a remineralizing solution (CaCl 2: 1.5 mM; KH2PO4: 5 mM; Acetic acid: 100 mM; NaCl: 100 mM; pH=6.5) at 37°C for 18 h. This procedure was repeated every day for 14 days 18) .…”
Section: Tooth Specimen Preparationmentioning
confidence: 99%
“…Artificial enamel lesions were created on tooth surfaces by immersion in a demineralizing solution (CaCl 2: 12 mM; KH2PO4: 10 mM; lactic acid: 50 mM; NaCl: 100 mM; pH=4.5) at 37°C for 6 h, followed by immersion in a remineralizing solution (CaCl 2: 1.5 mM; KH2PO4: 5 mM; Acetic acid: 100 mM; NaCl: 100 mM; pH=6.5) at 37°C for 18 h. This procedure was repeated every day for 14 days 18) .…”
Section: Tooth Specimen Preparationmentioning
confidence: 99%
“…Regarding children at high risk of developing early childhood caries (ECC), applying a toothpaste containing fluoride and xylitol compared to applying a toothpaste consisting of fluoride and sorbitol does not demonstrate a significant efficacy in reducing ECC [18]. However, in vitro studies suggest that combining fluoride and xylitol in toothpastes aids enamel remineralization [19]. Even so, in a metaanalysis by the ADA, it is stated that there is not enough evidence to acknowledge xylitol-containing dentifrices as preventing caries [14].…”
Section: Discussionmentioning
confidence: 99%
“…Dolay›s›yla minenin daha k›sa süreli asit ata¤›na maruz kalmas› ve yüksek pH de¤erleri mine demineralizasyonunu azaltaca-¤› ve hatta belki de remineralizasyon oluflturtaca¤› hipotezi öne sürülmüfltür. Önceki ça-l›flmalarda, ksilitol/NaF kombinasyonu (25) ve ksilitol ve florid içeren difl macunlar› (26) in vivo olarak remineralizasyonu artt›rmada faydal› bulunmufllard›r. Fakat her iki çal›flma-da da florid kullan›ld›¤›ndan ksilitolün etkisi de¤erlendirilememifltir.…”
Section: S Su Ub Bj Je Ec Ct Ts S a An Nd D M Me Et Th Ho Od Ds Sunclassified
“…Therefore, it was hypothesized shorter time that the enamel is affected by an acidic challenge and higher pH values would reduce enamel demineralization and perhaps even enhance remineralization. In previous studies xylitol/NaF combination (25) and xylitol and fluoride containing tooth pastes (26) were found to be useful to enhance remineralization in vivo. As fluoride was used in both studies, the effect of xylitol cannot be considered.…”
Section: S Su Ub Bj Je Ec Ct Ts S a An Nd D M Me Et Th Ho Od Ds Smentioning
confidence: 99%