Polycystic Ovary Syndrome -A metabolic malady the mother of all lifestyle disorders affecting mainly the women of childbearing age and teenage girls. India being the diabetic capital of world has close relation to PCOS metabolic syndrome comprising various frightening complications like overt diabetes, dyslipidemia, hypertension, endometrial cancer etc. According to W.H.O., PCOS affects 8 to 20 percent of women worldwide. In India, Department of Endocrinology and Metabolism AIIMS conducted a study which shows that about 20 to 25 percent of Indian women of reproductive age are suffering with PCOS. The etiology of this disease is now found to be both genetic and environmental. Obesity and insulin resistance is important target for preventive and therapeutic interventions. Therefore, life style modifications through diet and physical activity (Yoga therapy, meditation, pranayama, bio-purification procedures) are main stay of management. Healthy dietary interventions in the form of limited calories intake, avoidance of high carbohydrate diet, restricted fat intake, high fibrous diet, proper meal spacing and avoidance of junk food are very essential interventions to combat the weight gain. Physical activity in the form of yoga, brisk walking is essential modifiable life style component in its management. Studies have proved that 5 to 10 percent weight loss is enough to restore normal menstrual pattern and ovulation. Pranayama and meditation calms the mind which leads decrease level of depression, anxiety, stress level and self-esteem. Adopting all these interventions we can improve quality of life and can have better metabolic and reproductive outcome in women suffering from PCOS.