Effect of Acu-TENS therapy on Zhongwan (cv12) Acupoint in streptozotocin induced Diabetic Rats

Lakshmi, Subbu; Sivakumar, Girija; Murthy, Sathiya Narayana

doi:10.22376/ijpbs.2017.8.3.b1053-1058

Cited by 3 publications

(3 citation statements)

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“…The long term complications of diabetes lead to diseases of large blood vessels (macrovascular disease including coronary heart disease and peripheral arterial disease) and small blood vessels (microvascular disease, including retinal and renal vascular disease) 2 . Diabetes is a significant and growing threat to global health 3 .…”

Section: Quick Response Codementioning

confidence: 99%

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2020

IJPSR

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Section: Quick Response Codementioning

confidence: 99%

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2020

IJPSR

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“…With the suggested mechanism related to the decrease in IOP being the regained rebalance of qi (the Chinese traditional definition of energy or vital force passing through meridians) via stimulating specific acupoints on the body's surface, acupuncture is commonly used as an alternative treatment for POAG [18]. Despite the popular acupoint stimulation by manual or electro-acupuncture needling [19], both methods are invasive and consequently involve some injury risk. Non-invasive transcutaneous electrical nerve stimulation over acupoints (Acu-TENS) is supposed to produce the same effect of both methods [20], especially when used to treat eye disorders, such as glaucoma with IOP > 21 mmHg, related to the Bladder Meridian (BL) Foot-Taiyang [21].…”

Section: Introductionmentioning

confidence: 99%

Short-Term Intraocular Pressure Response to the Combined Effect of Transcutaneous Electrical Nerve Stimulation over Acupoint (Acu-TENS) and Yoga Ocular Exercise in Type 2 Diabetic Patients with Primary Open-Angle Glaucoma: A Randomized Controlled trial

Ismail

El-Azeim

2021

J Acupunct Meridian Stud

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Background: Despite the adherence to medications, the control of the modifiable key risk factor-intraocular pressure (IOP)-for the progression of primary open-angle glaucoma (POAG) in diabetics is usually difficult; hence, many glaucoma patients try other alternative therapeutic options. Objectives: This randomized controlled study investigated the short-term IOP response to the combined effects of transcutaneous electrical nerve stimulation over acupoint (Acu-TENS) and yoga ocular exercise in type 2 diabetics with POAG. Methods: Eighty diabetics with bilateral POAG, ages ≥ 50 years, IOP > 21 mmHg in both eyes, and a body mass index below 30 kg/m 2 were included in this trial. The patients were randomly assigned to group A (n = 40; this group received 20 minutes of yoga ocular exercise followed by 20 minutes of active Acu-TENS over bilateral BL 61 and BL 62 acupoints) and group B (n = 40; this group received the same protocol as group A but with a placebo Acu-TENS). The repeated measurement of IOP were recorded before, immediately after, 30 minutes, and 60 minutes after the sessions. Results:The repeated measures analysis of variance revealed a greater significant decline of IOP in group A than group B in both eyes at the consecutive intervals of time measurements. Conclusion:According to this short-term observation, the addition of Acu-TENS to yoga ocular exercise could reduce the high IOP in diabetic patients with POAG, but further longterm trials are needed.

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“…Diabetes is a chronic disorder characterized by altered metabolism in carbohydrates, fats and proteins with increased blood sugar levels. Macrovascular diseases (coronary heart disease and peripheral arterial disease) and microvascular diseases (retinal and renal vascular disease) are the long term complications of diabetes mellitus 1 . The Worldwide prevalence of diabetes will expect to increase from 4% in 1995 to 5.4% by the year 2025 2 and will become a growing threat to global health 3 .…”

Section: Introductionmentioning

confidence: 99%

Microanatomical Changes of Pancreas With Effect of Acutens at Zusanli (St36) Acupoints in Streptozotocin Induced Diabetic Rats

Lakshmi¹,

Sivakumar²,

Murthy³

2019

Int J Life Sci Pharm Res

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Acupuncture is an alternative and complementary medicine used throughout the World to treat various chronic disorders including diabetes. The aim of this present study is to explain the hypoglycemic effect of non-invasive stimulation with Acu-TENS at bilateral Zusanli (ST36) acupoints in Streptozotocin(45 mg /kg / body weight / IP) induced diabetic rats. The Acu-TENS therapy was given with low frequency 15 HZ, high intensity and width of 5 sec pulse at the Zusanli(ST36) acupoints in diabetic induced rats for 5 minutes every day without anaesthesia for 60 days. A more steady significant (p ≤ 0.01) decrease in fasting blood glucose level was noted in Zusanli acupoints treated diabetic rats and compared with antidiabetic drug (pioglitazone,7.5 mg / kg /body weight) treated rats.The acupuncture treated diabetic rats showed more significant (p ≤ 0.01) decrease in total cholesterol, triglycerides, low density lipid and significant increase in high density lipid.Histopathological examination of pancreas in Zusanli acupoints treated diabetic rats showed near normal architecture and regular shaped islets with regeneration of cells and compared with anti-diabetic drug treated rats pancreas. Stimulation at ST36 acupoints produced antidiabetic effects and improved lipid metabolism may be due to increase in insulin secretion through the mediation of β-endorphin and stimulation of Qi (energy flow) and utilisation of energy due to mild muscle twitching during stimulation.

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Effect of Acu-TENS therapy on Zhongwan (cv12) Acupoint in streptozotocin induced Diabetic Rats

Cited by 3 publications

References 6 publications

Untitled

Untitled

Short-Term Intraocular Pressure Response to the Combined Effect of Transcutaneous Electrical Nerve Stimulation over Acupoint (Acu-TENS) and Yoga Ocular Exercise in Type 2 Diabetic Patients with Primary Open-Angle Glaucoma: A Randomized Controlled trial

Microanatomical Changes of Pancreas With Effect of Acutens at Zusanli (St36) Acupoints in Streptozotocin Induced Diabetic Rats

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