Effect of Acute and Moderate Repeated Stress on Disturbances in Reactivity of Mesenteric Lymphatic Vessels during Inflammation in Rats

Abstract

We studied the effect of acute (single immobilization for 1 h) and repeated (daily immobilization for 1 min, 5 days) moderate stress on disturbances in contractility of mesenteric lymphatic vessels in rats with experimental peritonitis. Acute stress was shown to potentiate, while moderate repeated stress attenuate the effect of inflammatory stimulus. It can be hypothesized that moderate repeated stress improves adaptive capacities of the organism, which manifests in reduction or prevention of dysfunction in contractile activity of lymphatic vessels.

"Peritonitis: Relevance and Choice of Adequate Experimental Model"

“…1. Putting of foreign bodies [19] or injection of chemicals [20] into abdominal cavity of experimental animals.…”