Effect of acute kidney injury on weaning from mechanical ventilation in critically ill patients*

Vieira, J.M.; Castro, Isac de; Curvello-Neto, Américo; Demarzo, Sérgio Eduardo; Caruso, Pedro; Pastore, Laerte; Imanishe, Marina Harume; Abdulkader, Regina C. R. M.; Deheinzelin, Daniel

doi:10.1097/01.ccm.0000249828.81705.65

Cited by 204 publications

(140 citation statements)

References 33 publications

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“…When considering the sample's characteristics regarding male gender predominance, age and clinical diagnosis in the ICU hospitalization, pulmonary and cardiovascular diseases, the data was similar to that in the literature (9,(15)(16)(17) .…”

Section: Discussionsupporting

confidence: 67%

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Evolução clínica de pacientes com insuficiência renal aguda em unidade de terapia intensiva

et al. 2008

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Objective: To evaluate the clinical outcome of acute renal failure (ARF) patients when submitted to dialysis and non-dialysis treatments in ICU. Methods: this prospective study included patients over 18 years of age and serum creatinine of >1.5 mg/dl. The patients were included in dialysis and non-dialysis groups. Results: The study included 70 patients, 19 (27.1%) comprised the dialysis group and 51 (72.9%) the non-dialysis group. In the dialysis group, mortality rate was 42.1% and in the non-dialysis group was 33.3% (p<0.58). Conclusion: There were multifactors of ARF in ICU, but ARF is not the single cause for the high mortality rate in ICU patients. Keywords: Renal insufficiency, acute/therapy; Renal insufficiency, acute/epidemiology; Intensive care units; Nursing RESUMOObjetivo: Avaliar a evolução clínica de pacientes com insuficiência renal aguda (IRA) submetidos a tratamento dialítico e não-dialítico na UTI. Métodos: Estudo prospectivo onde foram incluídos pacientes com idade maior que 18 anos e com creatinina sérica > 1,5 mg/dl. Os pacientes foram divididos em grupo dialítico e não-dialítico. Resultados: Dos 70 pacientes incluídos 19 (27,1%) foram do grupo dialítico e 51 (72,9%) do grupo não-dialítico. A taxa de mortalidade foi de 42,1% no grupo dialítico e de 33,3% no grupo não-dialítico (p<0,58). Conclusão: Há multifatores determinando a IRA na UTI, porém, não é causa isolada das elevadas taxas de mortalidade dos pacientes na UTI. Descritores: Insuficiência renal aguda/terapia; Insuficiência renal aguda /epidemiologia; Unidades de terapia intensiva; Enfermagem RESUMEN Objetivo: Evaluar la evolución clínica de pacientes con insuficiencia renal aguda (IRA) sometidos a tratamiento dialítico y no-dialítico en la UCI. Métodos: Se trata de un estudio prospectivo donde fueron incluídos pacientes mayores de 18 años y con creatinina sérica > 1,5 mg/ dl. Los pacientes fueron divididos en grupo dialítico y no-dialítico. Resultados: De los 70 pacientes incluídos 19 (27,1%) fueron del grupo dialítico y 51 (72,9%) del grupo no-dialítico. La tasa de mortalidad fue del 42,1% en el grupo dialítico y del 33,3% en el grupo no-dialítico (p<0,58). Conclusion: Hay multifactores que determinan la IRA en la UCI, sin embargo, no es causa aislada de las elevadas tasas de mortalidad de los pacientes en la UCI.

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Section: Discussionsupporting

confidence: 67%

“…The studies show an association of a determined co-morbidity that may or may not affect the appearance of ARF in ICU (8,11,17) . In this study, the restrictive factor located was the small number of comorbidities that, when grouped, did not allow to identify them as a risk factor to ARF.…”

Section: Discussionmentioning

confidence: 99%

Evolução clínica de pacientes com insuficiência renal aguda em unidade de terapia intensiva

et al. 2008

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“…Other uremic manifestations may have several explanations (encephalopathy, acidosis) or may be occult causes of other complications (bleeding diathesis and gastrointestinal bleed, leukocyte dysfunction with immunosuppression and nosocomial infection). In addition to the emerging data that appear to confirm an independent role of AKI in increasing mortality in the ICU, it is also clinically obvious that AKI is a cause of significant morbidity and severely complicates ICU management (57).…”

Section: Pulmonary Effects Of Akimentioning

confidence: 99%

Mechanical Ventilation and Lung–Kidney Interactions

Koyner

Murray

2008

Clinical Journal of the American Society of Nephrology

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“…a smaller study, Vieira et al 8 found a link between acute kidney injury and unsuccessful weaning from mechanical ventilation resulting in increases in duration of mechanical ventilation, lengths of stay, and ICU mortality.…”

Section: Prime Pointsmentioning

confidence: 99%

Acute Renal Failure and Mechanical Ventilation: Reality or Myth?

Broden

2009

Critical Care Nurse

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Effect of acute kidney injury on weaning from mechanical ventilation in critically ill patients*

Abstract: This study shows that renal dysfunction has serious consequences in the duration of mechanical ventilation, weaning from mechanical ventilation, and mortality in critically ill cancer patients.

Cited by 204 publications

References 33 publications

Evolução clínica de pacientes com insuficiência renal aguda em unidade de terapia intensiva

Evolução clínica de pacientes com insuficiência renal aguda em unidade de terapia intensiva

Mechanical Ventilation and Lung–Kidney Interactions

Acute Renal Failure and Mechanical Ventilation: Reality or Myth?

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