Effect of AerobicandProgressive Resistance Training on Functional Capacity, Quality of Life and CD4 Count in People with HIV/AIDS

Vaiyapuri, Anandh; Peter, Ivor; Alagesan, Jagatheesan; Rajendran, Kishore

doi:10.15373/22778160/july2014/81

Cited by 7 publications

(7 citation statements)

References 12 publications

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“…Hence it is prove that statistically rehabilitation programme is effective to improve QOL in patients after 6 months. The findings supported by an experimental study conducted in Chennai which showed that the Mean ± SD for 3MST is 3.60 ± 0.63 and 4.33 ± 0.72 for before and after intervention respectively with p value equal to 0.001 proves statistically significant improvement in cardiovascular fitness after Progressive Resistance exercises for 3 months [10].…”

Section: Discussionsupporting

confidence: 69%

“…In this study, individually the effects of rehabilitation programme is assessed and proved there was marked improvement in functional wellbeing and positive changes in quality of life. Participation in an exercise programme modify the side effects of anti retro viral therapy and it is one key management to address impairment, activity limitation and participation restriction [10]. Four day weekly participation of Nurse directed rehabilitation programme for six months may be sufficient for improving the quality of life.…”

Section: Discussionmentioning

confidence: 99%

“…The experience of these symptoms negatively affects physical ability and consequently reduces quality of life, as patients experience limitations in their activities and participation.Participation in an exercise programme modifies the side effects of anti-retro viral therapy and quality of life may benefit [4].…”

Section: Introductionmentioning

confidence: 99%

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Effect of nurse directed rehabilitation programme on quality of life among patients with HIV attending care and support centers of Kottayam district, Kerala, South India

Itticheriya

2016

Public Health Rev: Int J Public Health Res

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Background: HIV has become a long-term condition, which not only affect the physical health, but also lead to psychological and social problems. Nurse directed rehabilitation programme may help people by improving their overall health and their ability to deal with stress. Objectives: To assess the pretest level of quality of life in both experimental and control group and to evaluate the effectiveness of nurse directed rehabilitation programme on quality of life. Methods: This is a randomized control study conducted at selected Care & Support Centers under the Medical College ART unit of Kottayam District. Purposive sampling was done for selection of care & support centers and simple random sampling for patients. 130 HIV infected patients were selected for the study and randomly divided into 2 groups with Mean ±SD age of 35.84±7.45years. Both groups were homogenous. Experimental group were given rehabilitation programme for 30 minutes 4 days / week for 6 months. QOL Scale (WHOQOLHIV-BREF) was used to assess quality of life and outcome of rehabilitation programme. Results: Findings show that there is mean quality of life (62.95) falls on the poor level among patient with HIV infection and 98% subjects experiences poor quality of life (χ 2 =0.341). Paired difference and t value proves that nurse directed rehabilitation programme highly significant in increasing quality of life (p<0.001) when compared with control group. Conclusion: The practice of nurse directed rehabilitation programme is effective as an adjunct therapy in patients with HIV infection that significantly improves the quality of life.

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Section: Discussionsupporting

confidence: 69%

Section: Discussionmentioning

confidence: 99%

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Effect of nurse directed rehabilitation programme on quality of life among patients with HIV attending care and support centers of Kottayam district, Kerala, South India

Itticheriya

2016

Public Health Rev: Int J Public Health Res

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“…There is evidence that cardiopulmonary function is significantly improved in patients with HIV infection by engaging in either aerobic exercises (jogging, brisk walking, stretching exercises, cycling, treadmill, and cross trainer - for 30–60 min, 3–5 times/week, at 40–80% max HR, or 50–80% VO 2 or 50% of LAT work rate or heavy aerobic – 50% difference between LAT and VO 2max on cycle ergometer) or resistance exercises (1–6 free weight exercises, 3 times/week, at 60–80% of 1 RM, 3–4 sets of 8–12 RM, or 60–80% V 2 peak and muscular endurance, for 30–60 min) or a combination of both exercises [aerobic exercise - 15 -20mins, at 50–70% of HRrest, plus resistance exercises (free weight and machine), 2–3 sets of 8–12 RM, for 3–5 times/week]. The findings from this study are very important because available evidence [86] suggests that co-morbidities that are associated with degeneration in HIV conditions are worsened by malnutrition, lack of physical exercise and restriction in social participation leading to multi-system (neurological, musculoskeletal, cardiopulmonary and metabolic) impairments. These conditions could minimisze functional mobility with adverse impact on socialiszation resulting in restricted social participation at the community level.…”

Section: Discussionmentioning

confidence: 82%

Effects of physical exercises on inflammatory biomarkers and cardiopulmonary function in patients living with HIV: a systematic review with meta-analysis

et al. 2019

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Background Pro-inflammatory cytokines expressed in human immune deficiency virus (HIV) infection, may induce oxidative stress likely to compromise the patency of the airways or damage the lung tissues/cardiac function. However, physical (aerobic and/or resistance) exercise-induced release of heat shock protein, immune function alteration or reduced tissue hypoxia, have been highlighted as possible mechanisms by which increasing physical activity may reduce plasma pro-inflammatory cytokines in uninfected individuals and should be appraised in the literature for evidence of similar benefits in people living with HIV (PLWH). Therefore, we evaluated the effects of physical exercises on 1) inflammatory biomarkers and 2) cardiopulmonary function (VO 2 Max) in PLWH. Method A systematic review was conducted using the Cochrane Collaboration protocol. Searching databases, up to January 2018. Only randomized control trials investigating the effects of either aerobic or resistance or a combination of both exercise types with a control/other intervention(s) for a period of at least 4 weeks among adults living with HIV, were included. Two independent reviewers determined the eligibility of the studies. Data were extracted and risk of bias (ROB) was assessed with the Cochrane Collaboration ROB tool. Meta-analyses were conducted with random effect models using the Review Manager (RevMan) computer software. Result Twenty-three studies met inclusion criteria ( n = 1073 participants at study completion) comprising male and female with age range 18–65 years. Three meta-analyses across three sub-groups comparisons were performed. The result showed no significant change in biomarkers of inflammation (IL-6 and IL-1β) unlike a significant (Z = 3.80, p < 0.0001) improvement in VO 2 Max. Overall, the GRADE evidence for this review was of moderate quality. Conclusion There was evidence that engaging in either aerobic or resistance exercise, or a combination of both exercises, two to five times per week can lead to a significant improvement in cardiopulmonary function but not biomarkers of inflammation (IL-6 and IL-1β). However, this should not be interpreted as “No evidence of effect” because the individual trial studies did not attain sufficient power to detect treatment effects. The moderate grade evidence for this review suggests that further research may likely have an important impact on our confidence in the estimate of effects and may change the estimate. Electronic supplementary material The online version of this article (10.1186/s12879-019-3960-0) contains supplementary material, which is available to authorized users.

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“…The results revealed differences between exercises (irrespective of whether they did STE or CTE) relative to non-exercisers with HIV. Moreover, randomized controlled trials evaluating exercise have primarily compared a non-exercising group against an exercising condition performing only one type of exercise, e.g., strength, aerobic, concurrent training, yoga, or tai chi as a single type of exercise intervention [42][43][44][45]. Yet, the daily experiences of professional trainers, physiologists, and physiotherapists have observed that people are participating in different types of recreational exercise during the course of a week.…”

Section: Discussionmentioning

confidence: 99%

Exercise, Comorbidities, and Health-Related Quality of Life in People Living with HIV: The HIBES Cohort Study

Zech

Schuch

Chaparro

et al. 2020

IJERPH

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(1) Background: People with HIV (PWH) may perform more than one type of exercise cumulatively. The objective of this study is to investigate recreational exercise and its association with health-related quality of life (HRQOL) and comorbidities in relation to potential covariates. (2) Methods: The HIBES study (HIV-Begleiterkrankungen-Sport) is a cross-sectional study for people with HIV. The differences between non-exercisers versus exercisers (cumulated vs. single type of exercises) were investigated using regression models based on 454 participants. (3) Results: Exercisers showed a higher HRQOL score compared to non-exercisers (Wilcox r = 0.2 to 0.239). Psychological disorders were identified as the main covariate. Participants performing exercise cumulatively showed higher scores in duration, frequency, and intensity when compared to participants performing only one type of exercise. The mental health summary score was higher for the cumulated and single type of exercise if a psychological disorder existed. Duration and intensity were associated with an increase of HRQOL, whilst a stronger association between psychological disorders and exercise variables were evident. Exercise duration (minutes) showed a significant effect on QOL (standardized beta = 0.1) and for participants with psychological disorders (standardized beta = 0.3), respectively. (4) Conclusions: Psychological disorders and other covariates have a prominent effect on HRQOL and its association with exercise. For PWH with a psychological disorder, a stronger relationship between HRQOL with exercise duration and intensity emerged. However, differentiation of high-HRQOL individuals warrants further investigation by considering additional factors.

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Effect of AerobicandProgressive Resistance Training on Functional Capacity, Quality of Life and CD4 Count in People with HIV/AIDS

Cited by 7 publications

References 12 publications

Effect of nurse directed rehabilitation programme on quality of life among patients with HIV attending care and support centers of Kottayam district, Kerala, South India

Effect of nurse directed rehabilitation programme on quality of life among patients with HIV attending care and support centers of Kottayam district, Kerala, South India

Effects of physical exercises on inflammatory biomarkers and cardiopulmonary function in patients living with HIV: a systematic review with meta-analysis

Exercise, Comorbidities, and Health-Related Quality of Life in People Living with HIV: The HIBES Cohort Study

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