Effect of Age on Cortical Activation during Swallowing: An fMRI Study

문현임, None; Pyun, Sung Bom; 태우석,; 정유진,; Choi, Sun-Young

doi:10.34160/jkds.2016.6.1.005

Cited by 7 publications

(1 citation statement)

References 21 publications

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“…Some authors have also highlighted age differences in brain cortical activation during swallowing. They found that older adults displayed larger neural activation particularly in the prefrontal cortex and middle temporal gyrus compared to younger adults, suggesting that swallowing may require greater neural control in this population (Humbert et al, 2009;Moon et al, 2016).…”

Section: How Can Neuroimaging Shed Light On the Conscious Aspect Of S...mentioning

confidence: 99%

Swallowing dysfunctions in patients with disorders of consciousness: Evidence from neuroimaging data, assessment, and management

Regnier,

Mélotte,

Aubinet

et al. 2024

NRE

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Following severe brain injuries, a subset of patients may remain in an altered state of consciousness; most of these patients require artificial feeding. Currently, a functional oral phase and the presence of exclusive oral feeding may constitute signs of consciousness. Additionally, the presence of pharyngo-laryngeal secretions, saliva aspiration, cough reflex and tracheostomy are related to the level of consciousness. However, the link between swallowing and consciousness is yet to be fully understood. The primary aim of this review is to establish a comprehensive overview of the relationship between an individual’s conscious behaviour and swallowing (reflexive and voluntary). Previous studies of brain activation during volitional and non-volitional swallowing tasks in healthy subjects are also reviewed. We demonstrate that the areas activated by voluntary swallowing tasks (primary sensorimotor, cingulate, insula, premotor, supplementary motor, cerebellum, and operculum) are not specific to deglutitive function but are shared with other motor tasks and brain networks involved in consciousness. This review also outlines suitable assessment and treatment methods for dysphagic patients with disorders of consciousness. Finally, we propose that markers of swallowing could contribute to the development of novel diagnostic guidelines for patients with disorders of consciousness.

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Section: How Can Neuroimaging Shed Light On the Conscious Aspect Of S...mentioning

confidence: 99%

Swallowing dysfunctions in patients with disorders of consciousness: Evidence from neuroimaging data, assessment, and management

Regnier,

Mélotte,

Aubinet

et al. 2024

NRE

View full text Add to dashboard Cite

show abstract

Esophageal Disease in Older Patients

DeVault

Achem

2021

The Esophagus

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Periventricular White Matter Lesions as a Prognostic Factor of Swallowing Function in Older Patients with Mild Stroke

et al. 2017

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Older patients with stroke have poor functional prognosis compared to younger patients. Patients with stroke who have severe white matter (WM) lesions have been reported to have poor functional prognosis such as cognitive dysfunction, increased propensity for falling, and gait and balance problems. The aim of this study was to determine whether WM lesions exert negative effects on swallowing function in older patients with mild stroke. We conducted a retrospective analysis of 63 patients aged >65 years who had a National Institutes of Health Stroke Scale score ≤5 and who underwent videofluoroscopic swallowing examination after their first stroke. Linear regression analysis showed that oral transit time tended to increase as Fazekas grade increased (p = 0.003). In addition, inadequate mastication was related to the presence of lesions in the left hemisphere (p = 0.039). The presence of penetration could also be predicted by Fazekas grade (p = 0.015). Our findings suggest that WM lesions observed in brain magnetic resonance imaging scans can impact swallowing problems in older patients with mild stroke, regardless of initial stroke severity or other factors associated with lesion location. Accordingly, our data indicate that WM lesions are a predictive factor by which patients can be stratified into favorable or unfavorable outcomes with respect to dysphagia.

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Effect of Age on Cortical Activation during Swallowing: An fMRI Study

Cited by 7 publications

References 21 publications

Swallowing dysfunctions in patients with disorders of consciousness: Evidence from neuroimaging data, assessment, and management

Swallowing dysfunctions in patients with disorders of consciousness: Evidence from neuroimaging data, assessment, and management

Esophageal Disease in Older Patients

Periventricular White Matter Lesions as a Prognostic Factor of Swallowing Function in Older Patients with Mild Stroke

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