2015
DOI: 10.1016/j.suc.2014.09.010
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Effect of Aging on Cardiac Function Plus Monitoring and Support

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Cited by 17 publications
(7 citation statements)
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“…arteries that lead to decreased compliance, stiffness, and eventual hypertension. 5 In addition, geriatric patients at baseline may have systolic and diastolic dysfunction 6 and a blunted response to adrenergic stimulation that may limit vasoconstriction 5,7 and the ability to mount a tachycardic response, 6,8 which is frequently magnified by the chronic use of betablocking agents in this population. These physiologic changes of aging are highlighted in our series as geriatric trauma patients more often presented with hypertension (30 vs 7%), cardiac disease (10 vs 1%), and cerebrovascular disease (4 vs 0.6%).…”
Section: Discussionmentioning
confidence: 99%
“…arteries that lead to decreased compliance, stiffness, and eventual hypertension. 5 In addition, geriatric patients at baseline may have systolic and diastolic dysfunction 6 and a blunted response to adrenergic stimulation that may limit vasoconstriction 5,7 and the ability to mount a tachycardic response, 6,8 which is frequently magnified by the chronic use of betablocking agents in this population. These physiologic changes of aging are highlighted in our series as geriatric trauma patients more often presented with hypertension (30 vs 7%), cardiac disease (10 vs 1%), and cerebrovascular disease (4 vs 0.6%).…”
Section: Discussionmentioning
confidence: 99%
“…As learned from patients with traumatic injury, the systolic BP threshold suggesting shock may begin at 110 mmHg in the elderly, rather than the usual 90 mmHg. As the elderly have reduced cardiovascular reserve, occult heart failure should not be forgotten; some drugs may affect heart rate, and it may be necessary to correct reduced contractility or afterload by means of vasopressors. This is best done by invasive monitoring and echocardiography in critical care, and should be prioritized early during resuscitation and preparation for surgery.…”
Section: Clinical Assessment and Preoperative Optimizationmentioning
confidence: 99%
“…Importantly, the consequences of these alterations do not appear at rest (Martin et al 2015). In contrast, during physical work the impairments in contractility in older adults lead to a diminished increase in ejection fraction by up to 20% and a consequent reduction in cardiac output compared with younger individuals (Hawkins and Wiswell 2003;Martin et al 2015).…”
Section: Systolic and Diastolic Functionmentioning
confidence: 99%
“…However, the age-related increase in resting sympathetic tone (i.e., reduced capacity to increase during stress) combined with the reduced sensitivity to changes in sympathetic stimulation limits the ability of the aging heart to increase heart rate during exertion (Hawkins and Wiswell 2003;Bellew et al 2005;Fleg et al 2005), which ultimately reduces the capacity to increase blood supply to the working muscles. Consequently, older adults rely more heavily on increasing stroke volume for increases in cardiac output relative to their younger counterparts (Martin et al 2015). Alternatively, changes in aging blood vessels can manifest as a marked reduction in elasticity (Greenwald 2007) and thereby increased stiffness, which leads to an increase in cardiac afterload.…”
Section: Cardiac and Vascular Responsivenessmentioning
confidence: 99%