1998
DOI: 10.1111/j.1600-0757.1998.tb00116.x
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Effect of aging on immunocompetent and inflammatory cells

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Cited by 35 publications
(45 citation statements)
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References 172 publications
(172 reference statements)
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“…The reduced expression patterns of IL-2 and IL-2R in peripheral monocytes of elderly patients have been reported as influencing the proliferative response of Tlymphocytes 46 . IL-2 is produced by helper T-cells and plays an important role in the proliferation and differentiation of virgin T-cells into effector T-cells (this term is used frequently for populations of T-cells with cytolytic activities and for T-helper cells, which secrete cytokines and activate directly other immune cells, to distinguish them from another class of T-cells known as regulatory T-cells) 47 . Ageing-related immunological alterations in the leukocyte subpopulations 48 and Blymphocyte subpopulations 49 have been reported.…”
Section: Immunosenescence and Periodontal Cells Interactionmentioning
confidence: 99%
“…The reduced expression patterns of IL-2 and IL-2R in peripheral monocytes of elderly patients have been reported as influencing the proliferative response of Tlymphocytes 46 . IL-2 is produced by helper T-cells and plays an important role in the proliferation and differentiation of virgin T-cells into effector T-cells (this term is used frequently for populations of T-cells with cytolytic activities and for T-helper cells, which secrete cytokines and activate directly other immune cells, to distinguish them from another class of T-cells known as regulatory T-cells) 47 . Ageing-related immunological alterations in the leukocyte subpopulations 48 and Blymphocyte subpopulations 49 have been reported.…”
Section: Immunosenescence and Periodontal Cells Interactionmentioning
confidence: 99%
“…3,4 It has been suggested that abnormal higher interleukin-6 levels may be related to the pathogenesis of periodontal diseases in the elderly. 3 Among individuals undergoing dialysis serum OPG levels were observed to be higher in elderly patient than in adult patients. 5 It has also been shown that serum OC levels generally increased with age in postmenopausal women.…”
Section: Introductionmentioning
confidence: 99%
“…For bone remodeling cycle activity ALP, OC, OPN, OPG and PTH were investigated in systemic bone changes Aging is associated with a decrease in mental and physical health and an increase in the risk of chronic diseases, such as atherosclerosis, cancer, diabetes and periodontitis. 3,4 It also affect the human immune response, particulary the T-lymphocyte system regarding to diminished count of T-cells in blood cells. 3,4 It has been suggested that abnormal higher interleukin-6 levels may be related to the pathogenesis of periodontal diseases in the elderly.…”
Section: Introductionmentioning
confidence: 99%
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