Indoor thermal environment of a 3-D ventilated room was studied by computational fluid dynamics to understand correlations between heat generation, ventilation velocity and thermal sensation indices. The existence of a thermal occupant was found to produce thermal plume approx stronger in magnitude than that from an unoccupied room. With second thermal occupant, there has further temperature increase of maximum , equivalent to an increase of PPD value by , for which occupants would normally feel uncomfortable.Thus, an increased flow ventilation rate ( ) would be required, in order to keep the same thermal comfort level of the room.