Effect of Alcohol Detoxification Beverage that Contained Bulnesia sarmienti on Alcohol-metabolizing Enzymes and Antioxidant Enzyme Activities

Lim, Ae-Kyung; Jung, Mee-Jung; Lee, Jae-Wook; Hong, Joo-Heon; Kim, Kil-Soo; Jung, Seok-Bang; Kim, Daeik

doi:10.11002/kjfp.2011.18.3.407

Cited by 3 publications

(1 citation statement)

References 11 publications

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“…These results were similar to those of our previous study on the effects of A. quinata extracts on alcohol induced hepatotoxicity using mice, which confirmed that the hepatoprotective effects of A. quinata can be applied to the human system ( 17 ). Numerous agents like plant extracts have been proposed for the treatment of alcoholic hangover, and some plant extracts have shown remarkable effects ( 22 – 24 ). In our study results, even though the reduction of plasma ethanol concentration was less than in other studies ( 9 ) and there were no significant differences from the control group, the participants had substantially reduced plasma ethanol concentrations, which have not been confirmed in a human-based study.…”

Section: Resultsmentioning

confidence: 99%

Effect of Beverage Containing Fermented Akebia quinata Extracts on Alcoholic Hangover

Jung¹,

Lee²,

Song³

et al. 2016

JFN

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The present study was conducted to investigate the effects of beverages containing fermented Akebia quinata extracts on alcoholic hangover. For this study, 25 healthy young men were recruited. All participants consumed 100 mL of water (placebo), commercial hangover beverage A or B, fermented A. quinata leaf (AQL) or fruit (AQF) extract before alcohol consumption. After 1 h, all participants consumed a bottle of Soju, Korean distilled liquor (360 mL), containing 20% alcohol. Blood was collected at 0 h, 1 h, 3 h, and 5 h after alcohol consumption. The plasma alanine transaminase (ALT) activity was highest in the placebo group. Compared with the control group, the AQL and AQF groups showed decreased ALT activity at 5 h after alcohol consumption. Plasma ethanol concentration was increased after alcohol intake and peaked at 3 h after alcohol consumption. Compared with the control group, the A group showed a higher plasma ethanol concentration at 1 h (P<0.05). At 3 h after alcohol consumption, the AQF group showed the lowest mean plasma ethanol concentration compared to the other groups; however, there were no statistical differences. After 5 h of alcohol consumption, the AQL and AQF groups showed lower plasma ethanol concentrations compared with the B group. The sensory evaluation score for the fermented A. quinata fruit extract was lower than for the commercial hangover beverages. In conclusion, the present intervention study results suggest that fermented A. quinata extracts alleviate alcoholic hangover and reduce plasma ethanol concentrations.

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Section: Resultsmentioning

confidence: 99%

Effect of Beverage Containing Fermented Akebia quinata Extracts on Alcoholic Hangover

Jung¹,

Lee²,

Song³

et al. 2016

JFN

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Effects of Polygoni Multiflori Radix on prevention of hyperlipidemia and liver damage induced by alcohol

Jang¹,

Park²,

Roh³

et al. 2015

The Korea Journal of Herbology

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Objectives : The Korean medical doctors use PMR(Polygoni Multiflori Radix) for nourishing the liver-kidney, loosing the bowel to relieve constipation, recovering from malaria, and clearing away heat and eliminating toxin, etc. But, this study was performed to investigate the effect of water extracts from PMR on prevention of hyperlipidemia and liver damage induced by alcohol. Methods ： Except for the normal group, we fed rat on 25% alcohol for 55 days. And the extract was administrated for the same period. We measured the serum components in rat's blood, body weight and weight of liver. Results ： At first, we observed effects of PMR on prevention of hyperlipidemia induced by alcohol. PMR group showed significant decrease of total cholesterol and triglyceride in comparison with those of the control group. PMR group showed significant increase of body weight in comparison with those of the control group in 4weeks and 8weeks. At second, we observed effects of PMR on prevention of liver damage induced by alcohol. PMR group showed significant decrease of GOT, GPT, ALP, and LDH in comparison with those of the control group. PMR group showed significant increase of liver weight in comparison with those of the control group. Conclusions ： Reviewing these experimental results, it appears that water extracts from PMR have pharmaceutical efficacy on prevention of hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of these.

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Anti-hangover and Anti-gout Effects of Asparagus Byproduct Extracts

Seo¹,

Yu²,

Lee³

et al. 2022

KJMCS

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Effect of Alcohol Detoxification Beverage that Contained Bulnesia sarmienti on Alcohol-metabolizing Enzymes and Antioxidant Enzyme Activities

Cited by 3 publications

References 11 publications

Effect of Beverage Containing Fermented Akebia quinata Extracts on Alcoholic Hangover

Effect of Beverage Containing Fermented Akebia quinata Extracts on Alcoholic Hangover

Effects of Polygoni Multiflori Radix on prevention of hyperlipidemia and liver damage induced by alcohol

Anti-hangover and Anti-gout Effects of Asparagus Byproduct Extracts

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