Effect of Alcohol‐Induced Septal Ablation on Left Atrial Volume and Ejection Fraction Assessed by Real Time Three‐Dimensional Transthoracic Echocardiography in Patients with Hypertrophic Cardiomyopathy

Hage, Fadi G.; Karakuş, Gültekin; Luke, William D.; Suwanjutah, Thouantosaporn; Nanda, Navin C.; Aqel, Raed

doi:10.1111/j.1540-8175.2008.00735.x

Cited by 18 publications

(9 citation statements)

References 17 publications

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“…63 As a consequence, the left atrial pressure and volume decrease in the first 3 months after PTSMA, with a simultaneous increase in left atrial ejection fraction that correlates with the LVOT gradient reduction. 64 …”

Section: Septal Ablation In Hcmmentioning

confidence: 99%

A Decade of Percutaneous Septal Ablation in Hypertrophic Cardiomyopathy

Rigopoulos

Seggewiß

2011

Circ J

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Percutaneous septal ablation has emerged as a less invasive treatment of symptomatic patients with hypertrophic obstructive cardiomyopathy (HOCM). In the past decade, the availability of this sophisticated technique has revived the interest of cardiologists in left ventricular outflow tract obstruction, which led to the recognition that most patients with HCM have the obstructive type. Follow-up studies have already shown the safety and efficacy of the procedure, which offers symptomatic relief in most patients. Long-term survival is comparable to historical reports after surgical myectomy. Complications are rare and can be further reduced with increased experience of the operators, and the theoretical concern for possible ventricular arrhythmogenicity of the myocardial scar has not been documented by the existing data. Although there are still no randomized trials, percutaneous septal ablation is undeniably a viable alternative for patients with HOCM. (Circ J 2011; 75: 28 - 37)

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Section: Septal Ablation In Hcmmentioning

confidence: 99%

A Decade of Percutaneous Septal Ablation in Hypertrophic Cardiomyopathy

Rigopoulos

Seggewiß

2011

Circ J

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“… 15 Follow‐up of cardiac function by 3DTTE after septal ablation has also been shown to be useful. In addition to the decrease in left ventricular outflow tract gradient, an improved left atrial end‐systolic volume and ejection fraction can be demonstrated with this technique 16 …”

Section: Hypertrophic Cardiomyopathymentioning

confidence: 95%

“…In addition to the decrease in left ventricular outflow tract gradient, an improved left atrial end-systolic volume and ejection fraction can be demonstrated with this technique. 16 Apical HCM is a nonobstructive variant of HCM that was first described in individuals of Japanese descent and has generally been associated with benign outcomes. 17 2DTTE has reduced utility in confirming this diagnosis due to limited visualization of the narrow apical cavity that is typical of this disorder ( Fig.…”

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confidence: 99%

Real Time Three‐Dimensional Echocardiography for the Evaluation of Cardiomyopathy

et al. 2012

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Cardiomyopathy refers to a set of diseases that are characterized by myocardial dysfunction. Classically, two-dimensional echocardiography has been used in the diagnosis of these disorders and to help guide their management. Three-dimensional transthoracic echocardiography is now increasingly being used in the diagnosis, management, and prognostication of intrinsic cardiomyopathies. In this article, we summarize the available data on the use of three-dimensional transthoracic echocardiography in various forms of intrinsic cardiomyopathy as well as some of its advantages over traditional two-dimensional transthoracic echocardiography.

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“…Septal ablation has been previously shown to result in the decrement of LA dimensions using 2-dimensional echocardiography. Hage et al [11 ]assessed the effects of PTSMA on LA volume and the LA ejection fraction using 3D echocardiography. They found that the LA volume was significantly reduced and the LA ejection fraction significantly increased in HOCM patients following septal ablation.…”

Section: Discussionmentioning

confidence: 99%

“…Percutaneous transluminal septal myocardial ablation (PTSMA) is an alternative therapy for patients with hypertrophic obstructive cardiomyopathy (HOCM) that results in long-term improvement in diastolic dysfunction and also partially reverses LA remodeling [9,10,11]. However, it is still uncertain whether PTSMA can reduce the risk of AF in HOCM patients.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Atrial Conduction Abnormalities in Patients with Hypertrophic Cardiomyopathy Before and One Year after Alcohol Septal Ablation

Shi¹,

Yuan²,

Zhang

et al. 2012

Cardiology

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Objectives: Intra- and interatrial electromechanical delay (AEMD) can be used to evaluate the development of atrial fibrillation (AF). Percutaneous transluminal septal myocardial ablation (PTSMA) is an alternative therapy for patients with hypertrophic obstructive cardiomyopathy (HOCM) that results in sustained improvements in atrial structure and function. We investigated the effects of PTSMA on the intra- and inter-AEMD of HOCM patients using tissue Doppler imaging. Methods: Conventional echocardiographic and AEMD parameters were obtained in 25 healthy controls and 31 HOCM patients before and 1 year after septal ablation procedures. Results: Compared with the healthy controls, the left atrial volumes indexed by body surface area (LAVI) and the intra- and inter-AEMD were significantly higher in the HOCM patients. At 1 year after PTSMA, the LAVI was decreased (37.2 ± 11.4 to 27.0 ± 8.5 ml/m², p < 0.001). The intra- and inter-AEMD were also significantly decreased (22.7 ± 9.2 to 16.6 ± 7.7 ms, p < 0.001 and 37.0 ± 8.4 to 26.6 ± 8.0 ms, p < 0.001, respectively). These changes correlated well with the reductions in LAVI (r = 0.83, p < 0.001; r = 0.66, p < 0.001). Conclusions: Both the intra- and inter-AEMD were significantly prolonged in the HOCM patients. PTSMA can improve the prolonged and inhomogeneous propagation of sinus impulses in atria.

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Effect of Alcohol‐Induced Septal Ablation on Left Atrial Volume and Ejection Fraction Assessed by Real Time Three‐Dimensional Transthoracic Echocardiography in Patients with Hypertrophic Cardiomyopathy

Cited by 18 publications

References 17 publications

A Decade of Percutaneous Septal Ablation in Hypertrophic Cardiomyopathy

A Decade of Percutaneous Septal Ablation in Hypertrophic Cardiomyopathy

Real Time Three‐Dimensional Echocardiography for the Evaluation of Cardiomyopathy

Assessment of Atrial Conduction Abnormalities in Patients with Hypertrophic Cardiomyopathy Before and One Year after Alcohol Septal Ablation

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