Effect of allyl propyl disulphide isolated from onion (Allium cepa L.) on glucose tolerance of alloxan diabetic rabbits

Augusti, K. T.; Roy, van; Semple, M.

doi:10.1007/bf01923642

Cited by 18 publications

(5 citation statements)

References 17 publications

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“…Onion feeding improved the metabolic status in diabetic conditions, probably because of hypoglycemic and hypocholesterolemic effect (Babu and Srinivasan, 1997), mediated diabetic nephropathy by lowering blood cholesterol levels and decreasing lipid peroxidation (Babu and Srinivasan, 1999). The research results about active principles showed that allyl propyldisulfide and S-methyl cysteine sulfoxide have an anti-diabetic and anti-hyperlipidemic effect, the latter being comparable to glibenclamide and insulin (Augusti et al, 1974;Sheela et al, 1995;Kumari et al, 1995).…”

Section: Allii Cepa Bulbusmentioning

confidence: 93%

Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus

Zheng

Bukuru

et al. 2004

Journal of Ethnopharmacology

805

524

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Section: Allii Cepa Bulbusmentioning

confidence: 93%

Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus

Zheng

Bukuru

et al. 2004

Journal of Ethnopharmacology

805

524

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“…[37] Its active principles showed that allyl propyl disulfide and S-methyl cysteine sulfoxide have an anti-diabetic and anti-hyperlipidemic effect, the latter being analogous to glibenclamide and insulin [Figure 2]. [38–40]…”

Section: Type 2 Diabetesmentioning

confidence: 99%

Functional herbal food ingredients used in type 2 diabetes mellitus

Perera¹,

Li²

2012

Phcog Rev

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From many reports it is clear that diabetes will be one of the major diseases in the coming years. As a result there is a rapidly increasing interest in searching new medicines, or even better searching prophylactic methods. Based on a large number of chemical and pharmacological research work, numerous bioactive compounds have been found in functional herbal food ingredients for diabetes. The present paper reviews functional herbal food ingredients with regards to their anti-diabetic active principles and pharmacological test results, which are commonly used in Asian culinary system and medical system and have demonstrated clinical or/and experimental anti-diabetic effectiveness. Our idea of reviewing this article is to give more attention to these functional food ingredients as targets medicinal foods in order to prevent or slow down the development of type 2 diabetes mellitus.

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“…Onion contains S methyl cysteine sulfoxide which is responsible for anti-diabetic activity. 77 Chromium improves glucose tolerance by decreasing insulin levels, fasting glucose levels, and lowering blood cholesterol and triglycerides (TG) levels. 78 Quercetin in allium cepa facilitates glucosemediated secretion of insulin by assisting phosphorylation of extracellular signal-regulated kinase and protecting pancreatic beta-cells and ultimately controls sugar-induced secretion of insulin, elevating the specific activity of several pancreatic islets and liver glucokinase (a carbohydrate enzyme) that facilitates improved glucose tolerance.…”

Section: Antidiabetic Activitymentioning

confidence: 99%

Green synthesis of silver nitrate (AgNO) mediated herbal antimicrobial aqueous extracts of Ocimum basilicum (Basil Leaves)

Rani

2023

IJCAAP

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Green antimicrobial herbal preparations have emerged as cost effective, non-toxic and sustainable approach that involves the use of eco-friendly and non-toxic plant herbs and spices extracts. Green synthesis of silver-treated herbal extracts of Ocimum basilicum (basil leaves extracts) is well known for its safe and cost-effective approach due to having antimicrobial activity to treat various influenza like symptoms, antistress and antidepressant properties. Herbal plant leaf extracts have also been reported to contain an active reducing agent that can reduce metal ions to synthesize biogenic metal nanoparticles. Silver itself, is well reported for their bactericidal properties and also enhance antimicrobial properties when used to prepare biogenic silver nanoparticles from herbal and other biological sources. Hence, we prepared silver nitrate (AgNO) mediated herbal formulations of (basil extracts) that showed significant antibacterial activity against gram-negative bacteria, Escherichia coli BL21 strain. Moreover, this green approach can be more promising to prepare antimicrobial of silver-treated formulations using Ocimum basilicum extracts. It might be safe and cost effective herbal based preparations including nanosuspensions that can further proposed for clinical practices to treat various microbial pathogenesis.

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Effect of allyl propyl disulphide isolated from onion (Allium cepa L.) on glucose tolerance of alloxan diabetic rabbits

Cited by 18 publications

References 17 publications

Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus

Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus

Functional herbal food ingredients used in type 2 diabetes mellitus

Green synthesis of silver nitrate (AgNO) mediated herbal antimicrobial aqueous extracts of Ocimum basilicum (Basil Leaves)

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