Effect of aminoglutehimide and reserpine on the human pituitary-adrenal axis: Remission of a case of Cushing's disease

Givens, James R.; Camacho, Alvro M.; Patterson, P.A.

doi:10.1016/0026-0495(70)90079-x

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Aminoglutethimide Pharmacological Properties1

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2007

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Cited by 8 publications

(1 citation statement)

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“…Recommended daily doses range from 0.5 to 2 g [154][155][156][157][158][159]. The agent is begun at a dose of 500 mg daily, in divided doses, and can be increased by 250 to 500 mg every three to four days.…”

Section: Aminoglutethimide Pharmacological Propertiesmentioning

confidence: 99%

Pharmacological Therapy of Cushings Syndrome: Drugs and Indications

Díez

Iglesias²

2007

MRMC

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Section: Aminoglutethimide Pharmacological Propertiesmentioning

confidence: 99%

Pharmacological Therapy of Cushings Syndrome: Drugs and Indications

Díez

Iglesias²

2007

MRMC

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Spontaneous Remission in Cushing's Disease

Dickstein

Spindel²,

Shechner³

et al. 1991

Arch Intern Med

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Spontaneous Remission in Cushing's Disease

Ishibashi

Shimada²,

Abe³

et al. 1993

Arch Intern Med

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Two patients with Cushing's disease underwent spontaneous clinical and biochemical remission following a period of secondary adrenal insufficiency. One of the patients was untreated, while the other had been treated with partial bilateral adrenalectomy before. Both patients underwent remission shortly after the administration of dexamethasone for diagnostic purposes and remained symptom free for 2 and 3 years, respectively, which was followed by relapse of the disease. We conclude that although resolution of Cushing's disease may occur spontaneously, probably by hemorrhagic infarction of corticotroph microadenomas, careful follow-up studies are required since the relapse of the disease occurs later in some patients.

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Effect of aminoglutehimide and reserpine on the human pituitary-adrenal axis: Remission of a case of Cushing's disease

Cited by 8 publications

References 11 publications

Pharmacological Therapy of Cushings Syndrome: Drugs and Indications

Pharmacological Therapy of Cushings Syndrome: Drugs and Indications

Spontaneous Remission in Cushing's Disease

Spontaneous Remission in Cushing's Disease

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