Effect of an herbal mouthwash on periodontal indices in patients with plaque-induced gingivitis: A cross-over clinical trial

Abstract

Background. Recent advances in alternative medicine have led to the introduction of various new herbal products for treating gingivitis as the most prevalent gingival disease. The present study clinically evaluated the effect of a herbal mouthwash consisting of 5 herbal extracts (Myrtus communis, Quercus brantii, Punica granatum, Portulaca olerace, and Boswellia serrata) on periodontal indices. Methods. Fifty patients with plaque-induced gingivitis were included in this randomized, dou­ble-blinded clinical trial and divided into two groups. Following scaling and root planing (SRP), they were prescribed 0.2% chlorhexidine (CHX) (group 1) and herbal mouthwash (group 2) twice a day for 14 days. Both groups received saline mouthwash for the subsequent 14 days (wash-out time). Then, they used the mouthwashes in a cross-over manner for an additional two weeks. Probing pocket depth (PPD), gingival index (GI), bleeding on probing (BOP), and plaque index (PI) were recorded at baseline and after each period of mouthwash use. The data were analyzed by SPSS software, using generalized estimating equation (GEE) linear regression and paired t-test. P<0.05 was considered sta­tistically significant. Results. Both groups exhibited statistically significant improvements in the periodontal indices compared to the baseline (P<0.05); however, there were no significant differences between the two study groups in this regard. Conclusion. The experimental herbal mouthwash improved the periodontal condition in plaque-induced gingivitis after two weeks, comparable to the effect of %0.2 CHX mouthwash in terms of PPD, BOP, PI, and GI.

Frankincense (Boswellia serrata) Extract Effects on Growth and Biofilm Formation of Porphyromonas gingivalis, and Its Intracellular Infection in Human Gingival Epithelial Cells

“…Several studies describe clinical trials using frankincense extracts to treat several conditions, such as knee pain [59,60], hepatic inflammation and lipid metabolism [61], and chronic low back pain [62]. Regarding oral health, three publications report the effects of B. serrata extracts in the treatment of periodontitis [63][64][65]. Ardakani et al showed that patients using a mouthwash consisting of five herbal extracts (including B. serrata extracts) improved their periodontal condition in plaque-induced gingivitis comparable to the effect of 0.2% chlorhexidine mouthwash [63].…”

“…Regarding oral health, three publications report the effects of B. serrata extracts in the treatment of periodontitis [63][64][65]. Ardakani et al showed that patients using a mouthwash consisting of five herbal extracts (including B. serrata extracts) improved their periodontal condition in plaque-induced gingivitis comparable to the effect of 0.2% chlorhexidine mouthwash [63]. However, because the authors used a mix of five natural products, it is not possible to conclude whether B. serrata extracts play a role in the improvement of clinical symptoms.…”

The relationships of inflammatory blood markers with maternal periodontal and dental states and their effects on preterm membrane rupture development

“…Measures such as GI, PI and PD play a fundamental role in the assessment of gum health. These indices provide information about the reality and prevalence of gum disease and are important in the development of treatment plans [ 37 ]. It was observed that these measurements were higher in the case group compared to the control group.…”

Chamomile tea decreases Porphyromonas gingivalis viability

“…6,7 Chamomile mouthwashes are even comparable to scaling and root planning or the use of 0.2% chlorhexidine in the treatment of periodontitis. 8,9 Porphyromonas gingivalis is a major player in the pathogenesis of periodontal disease. We have evaluated the antimicrobial activity of chamomile tea on P. gingivalis in vitro.…”

“…6,7 Chamomile mouthwashes are even comparable to scaling and root planning or the use of 0.2% chlorhexidine in the treatment of periodontitis. 8,9…”