Effect of Anesthetics Containing Lidocaine and Epinephrine on Cardiovascular Changes During Dental Implant Surgery

Abstract

The purpose of this study was to evaluate cardiovascular changes during dental implant surgery using 2% lidocaine with 1:80 000 epinephrine. Eleven normotensive subjects, ranging from 18 to 56 years, were selected to undergo dental implant surgery in the jaw. They were monitored in the pre-, intra-, and postsurgical periods by continuous noninvasive automatic arterial pressure and cardiac frequency measurements taken every 2 minutes. Parameter scores were obtained for the following phases: P1, 15 minutes during preparation of the patient (control period); P2, before anesthesia; P3, immediately after anesthesia; P4, 2 minutes into anesthesia; P5, during incision and detachment; P6, during perforation; P7, during implant placement; P8, during suturing; P9, on completion; and P10, 10 minutes after termination. Individualized statistical analysis for each group during the pre-, intra-, and postoperative periods were performed by analysis of variance. The greatest variations in systolic pressure were increases of 2.29% during phase P2 and 2.59% in phase P5. Diastolic pressure decreased during phase P6 (-2.58%) and increased in P10 (3.27%). The greatest changes in heart rate occurred in phase P10 (-3.24%). There were no statistically significant changes among the evaluated phases (P > .05). In conclusion, there were no changes in the analyzed cardiocirculatory parameters during dental implant surgery (systolic, diastolic, and mean arterial blood pressures and heart rate) in normotensive subjects anesthetized with 2% lidocaine with epinephrine 1:80000.

Hemodynamic Changes Following Intraoral Injection of Lidocaine in Combination With Adrenaline During Tooth Extraction

“…In the current study, the measured parameters returned back to baseline reading 10 minutes after the completion of tooth extraction as the stress and fear induced by surgical procedure, were terminated 16 . Furthermore, In the current study, we found that diastolic blood pressure increased at 10 minutes post local anaesthetics injection in a similar way to systolic blood pressure but to less extent, this finding is in agreement with previous studies 5, 20,21 . There was a significant increase of heart rate during extraction in both groups as compared to their corresponding baseline values; However, the differences between the normotensive and hypertensive were not significant.…”

Evaluation of hemodynamic and SpO2 variability during different stages of periodontal surgery

“…survey on the effect of anesthetics containing lidocaine and epinephrine on cardiovascular changes during dental implant surgery, blood pressure was evaluated using the automated noninvasive oscillometric technique during ten steps; the results showed no significant difference in blood pressure and heart rate variability,[7] which is not in accordance to the findings achieved in this research.…”

“…In spite of the effect of local anesthetics on vital signs, their accurate application is able to dramatically reduce stress. [7]…”

Non-linear indices of heart rate variability during endodontic treatment

“…23,24,25 Anxiety and fear of endodontic treatment were reported by a large number of patients during this study. These emotions can generate significant autonomic changes and determine physiological changes related to sympathetic nervous system activity, expressed as pallor, sweating palms, t rembli ng, com mun icat ion di fficult ies a nd tachycardia.…”