Effect of anisotropy and drying of costal cartilage on its optical transmittance in laser reshaping of implants with 1, 2, and 3 mm in thickness

Soshnikova, Yulia M.; Keselman, M. M.; Baum, Olga I.; Shults, Elvira V.; Обрезкова, М. В.; Лунин, В. В.; Sobol, Emil N.

doi:10.1002/lsm.22575

Cited by 7 publications

(3 citation statements)

References 19 publications

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“…For transferring these novel technologies from tests on phantoms and excised tissue samples to in vivo ophtalmological applications, a key point is to ensure safety of the treatment (avoiding overheating) and the possibility to visualize dynamic strains in real time together with the resultant shape of the tissue. Similar issues are very important in the fabrication of cartilaginous implants (typically with ~mm-scale thickness) for otolaryngology [8,9].…”

Section: Introductionmentioning

confidence: 99%

Optical coherence tomography for visualizing transient strains and measuring large deformations in laser-induced tissue reshaping

et al. 2016

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In the context of the development of emerging laser-assisted thermo-mechanical technologies for non-destructive reshaping of avascular collagenous tissues (cartilages and cornea), we report the first application of phase-sensitive optical coherence tomography (OCT) for visualizing transient strains involving supra-wavelength inter-frame displacements of scatterers. Usually phase-sensitive OCT assumes the visualization of sub-pixel and even sub-wavelength displacements of scatterers and fairly small strains (say, <10−3), which conventionally implies the necessity of averaging for enhancing the effective signal-to-noise ratio and, correspondingly, the application of small-amplitude actuators producing periodic deformations. The original approach used here allows for direct estimation of elevated strains ~10−2 (close to onset of intense speckle blinking) obviating the necessity of averaging and phase unwrapping for supra-wavelength inter-frame displacements. We demonstrate the possibility of mapping aperiodic thermally-induced transient strains with resultant large deformations on order of tens per cent. Such strains are typical in laser tissue reshaping, but are far beyond the range of conventionally discussed OCT-based strain mapping.

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Section: Introductionmentioning

confidence: 99%

Optical coherence tomography for visualizing transient strains and measuring large deformations in laser-induced tissue reshaping

et al. 2016

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“…The stable semicircle shape of cartilage reflects the tracheal curvature and is aimed to prevent airway narrowing, which is the life-threatening adverse effect in trachea stenosis surgery [14]. Analyzing the obtained effect for implants of different thickness we showed that well-controlled heating through the whole thickness of an implant is crucial for the new shape stability [15]. Simultaneously, the very local heating of cartilage by separate laser spots is needed to avoid thermal injury of matrix and cells [9,10].…”

Section: Introductionmentioning

confidence: 99%

“…But the attempts to heat the deep tissue layers of thicker implants may cause the superficial burn and substantially disturb the safety of the procedure. On the contrary, thin cartilage implants transmit a lot of laser energy and possess high residual stress that disrupts the stability of the new shape .…”

Section: Introductionmentioning

confidence: 99%

Controlling the near‐infrared transparency of costal cartilage by impregnation with clearing agents and magnetite nanoparticles

Alexandrovskaya

Sadovnikov

Sharov

et al. 2017

Journal of Biophotonics

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Penetration depth of near-infrared laser radiation to costal cartilage is controlled by the tissue absorption and scattering, and it is the critical parameter to provide the relaxation of mechanical stress throughout the whole thickness of cartilage implant. To enhance the penetration for the laser radiation on 1.56 μm, the optical clearing solutions of glycerol and fructose of various concentrations are tested. The effective and reversible tissue clearance was achieved. However, the increasing absorption of radiation should be concerned: 5°C-8°C increase of tissue temperature was detected. Laser parameters used for stress relaxation in cartilage should be optimized when applying optical clearing agents. To concentrate the absorption in the superficial tissue layers, magnetite nanoparticle (NP) dispersions with the mean size 95 ± 5 nm and concentration 3.9 ± 1.1 × 10 particles/mL are applied. The significant increase in the tissue heating rate was observed along with the decrease in its transparency. Using NPs the respective laser power can be decreased, allowing us to obtain the working temperature locally with reduced thermal effect on the surrounding tissue.

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Cartilage Reshaping

Gu¹,

Wong²

2020

Lasers in Oral and Maxillofacial Surgery

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Effect of anisotropy and drying of costal cartilage on its optical transmittance in laser reshaping of implants with 1, 2, and 3 mm in thickness

Cited by 7 publications

References 19 publications

Optical coherence tomography for visualizing transient strains and measuring large deformations in laser-induced tissue reshaping

Optical coherence tomography for visualizing transient strains and measuring large deformations in laser-induced tissue reshaping

Controlling the near‐infrared transparency of costal cartilage by impregnation with clearing agents and magnetite nanoparticles

Cartilage Reshaping

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