2023
DOI: 10.15574/ps.2023.78.72
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Effect of anti-adhesion agents on cytokine profile in an experimental model of postoperative intra-abdominal adhesions

Abstract: Many attempts have been made to prevent peritoneal adhesions using anti-adhesion agents, barriers and other therapeutic approaches, but their efficacy has not been widely accepted. Purpose – to determine the effects of mezogel, a mixture of metronidazole, dextran, and contrykal enriched with oxygen based on the pro- and anti-inflammatory cytokine concentration in rats with simulated postoperative peritoneal adhesions. Materials and methods. A total of 90 outbred white rats, divided into three groups of 30 anim… Show more

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